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Browse our INHBB Proteins (INHBB)

Full name:
Inhibin, beta B Proteins (INHBB)
On are 28 Inhibin, beta B (INHBB) Proteins from 9 different suppliers available. Additionally we are shipping INHBB Antibodies (119) and INHBB Kits (38) and many more products for this protein. A total of 193 INHBB products are currently listed.
actbb, actbetaB, inhibin
list all proteins Gene Name GeneID UniProt
INHBB 25196 P17491
INHBB 16324 Q04999
INHBB 3625 P09529

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INHBB Proteins (INHBB) by Origin

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More Proteins for INHBB Interaction Partners

Zebrafish Inhibin, beta B (INHBB) interaction partners

  1. The present study demonstrated that EGF (show EGF Proteins) controlled expression of three activin subunits (inhbaa (show INHBA Proteins), inhbab and inhbb) in the follicle cells via diverse signaling pathways.

  2. whereas the inhibitory effect of hCG (show CGA Proteins) on activin betaB expression is likely mediated by PKA-independent pathway(s).

  3. Activin betaA is involved in promoting ovary and follicle growth, whereas activin betaB may have a tonic role throughout follicle development but becomes critical at the late stage of oocyte maturation and/or ovulation.

Xenopus laevis Inhibin, beta B (INHBB) interaction partners

  1. point mutation enhances the affinity of Noggin2 to ActivinB, while weakens its affinity to BMP.

  2. Noggin2 protected the developing forebrain from inhibition by Activin B and XWnt8 (show WNT8A Proteins) signaling.

  3. A new role for activin B during gastrulation involves cell cycle arrest in the involuting dorsal axial mesoderm.

  4. Used monoclonal antibody to xenopus laevis Inhbb in ELISA for detection of human Inhbb.

Mouse (Murine) Inhibin, beta B (INHBB) interaction partners

  1. Menin (show MEN1 Proteins) binds on the promoter of Inhbb gene where it favours the recruitment of Ezh2 (show EZH2 Proteins) via an indirect mechanism involving Akt (show AKT1 Proteins)-phosphorylation.

  2. Data suggest Inhbb is physiologically essential for early folliculogenesis; Inhbb appears to participate in regulation of cell cycle progression, apoptosis, and steroidogenesis (estradiol/progesterone synthesis) in ovarian granulosa cells in culture.

  3. Activin B, a transforming growth factor beta - related ligand, is upregulated during tumorigenesis and drives the loss of insulin (show INS Proteins) expression and beta-cell maturity in a mouse insulinoma (show RPS15 Proteins) model.

  4. in mammalian spinal cord, Tgfbeta (show TGFB1 Proteins) ligands and ActB (show ACTB Proteins) together support oligodendrocyte development and myelin formation

  5. No differences were observed in fasting glucose/insulin levels, glucose tolerance, insulin sensitivity, or insulin secretion in comparing young or older males on in comparing insulin secretion from islets of wild type or activin B knockout males.

  6. There is a dramatic induction of Inhbb mRNA, e (show HAMP Proteins)ncoding the activin beta(B)-subunit, in liver challenged with lipopolysaccharide, slightly preceding an increase in Smad1/5/8 phosphorylation and Hamp m (show HAMP Proteins)RNA.

  7. the transition between stem cells and committed progenitors is neither sharp nor irreversible and GDF11 (show GDF11 Proteins), ACTbetaB and FST (show FST Proteins) are crucial components of a circuit that controls both total cell number and the ratio of neuronal versus glial cells in this system

  8. These data support the role of proconvertase PCSK5 in the processing of ovarian inhibin subunits during folliculogenesis.

  9. Maintenance of female germ cells hinge upon a delicate balance between positive (WNT4 (show WNT4 Proteins) and beta-catenin (show CTNNB1 Proteins)) and negative (activin betaB) regulators derived from the somatic cells in the fetal ovary.

  10. Inhbb-deficient mice have failure of eyelid fusion at birth and demonstrate more severe effects on somatic growth and survival.

Human Inhibin, beta B (INHBB) interaction partners

  1. Results identified Inhbb as one factor mediating the proliferative effect of Pdx-1 (show PDX1 Proteins) on islet cells.

  2. Low activin B level is associated with tubal ectopic pregnancy.

  3. The Sertoli cell hormones inhibin-B and anti Mullerian hormone (show AMH Proteins) have different patterns of secretion in prepubertal cryptorchid boys.

  4. Pregnant Han Chinese women carrying the rs7579169 CC genotype and G-G-C haplotype are significantly more likely to develop pre-eclampsia, especially late-onset and multiparous cases.

  5. We report here an original observation that activin-B is upregulated in the human idiopathic pulmonary fibrosis lung.

  6. reduction of RhoA (show RHOA Proteins) signaling by Activin B together with persistent Rac1 activity is a prerequisite for inducing an invasive phenotype in clear cell renal cell carcinoma (show MOK Proteins).

  7. inhibin B and anti-Mullerian hormone (show AMH Proteins) serum concentrations did not provide an additional diagnostic tool for male infertility

  8. Activin-A (show INHBA Proteins) and -B are abundantly expressed in mesothelioma tumor tissue.

  9. Activin A, B, and AB have similar effects on steroidogenesis in human granulosa cells; in contrast, activin AC is not biologically active and does not act as a competitive antagonist.

  10. Serum inhibin levels correlate with clinical characteristics and mortality in epithelial ovarian cancer patients.

Pig (Porcine) Inhibin, beta B (INHBB) interaction partners

  1. An increased expression of Inhibin-beta B was found in oocytes collected from large and medium follicles compared with small follicles before or after in oocyte vitro maturation.

  2. our data indicate that miR (show MYLIP Proteins)-34a plays an important role in granulosa cell apoptosis by targeting the INHBB gene in the porcine ovary

  3. results indicated that boar testis produces inhibin A and inhibin B during the infantile period but inhibin A is the predominant form towards puberty and molecular weight forms of inhibin and the sites of production change with testicular development

INHBB Protein Profile

Protein Summary

The inhibin beta B subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumour-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the beta B subunit forms a homodimer, activin B, and also joins with the beta A subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion.

Alternative names and synonyms associated with INHBB

  • inhibin, beta B (inhbb)
  • inhibin, beta B (INHBB)
  • inhibin beta-B (Inhbb)
  • inhibin, beta B (Inhbb)
  • actbb protein
  • actbetaB protein
  • inhibin protein

Protein level used designations for Inhibin, beta B Proteins (INHBB)

activin beta B , activin B , activin beta B subunit , inhibin, beta B , inhibin beta B , inhibin, beta B (activin AB beta polypeptide) , inhibin beta B chain-like , activin beta-B chain , activin betaB , inhibin beta B chain , inhibin beta subunit B , Inhibin, beta-2 , activin AB beta polypeptide , inhibin beta-(b) subunit , betaB inhibin/activin , inhibin beta B subunit

30275 Danio rerio
399280 Xenopus laevis
493742 Felis catus
574343 Macaca mulatta
100124901 Xenopus (Silurana) tropicalis
100484001 Ailuropoda melanoleuca
25196 Rattus norvegicus
16324 Mus musculus
3625 Homo sapiens
396126 Gallus gallus
397490 Sus scrofa
530430 Bos taurus
100719829 Cavia porcellus
100861250 Capra hircus
101119286 Ovis aries
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