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Second Mitochondria-Derived Activator of Caspase (DIABLO) (C-Term) Peptide

Details for Product No. ABIN1382084, Supplier: Login to see
Protein Name
  • smac
  • smac3
  • diablo-s
  • 0610041G12Rik
  • 1700006L01Rik
  • AU040403
  • Smac
  • DFNA64
  • SMAC
  • DBO
  • XSmac
Protein Region
C-Term
Origin
Mouse (Murine)
5
Application
Blocking Peptide (BP)
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Blocked Antibody anti-Second Mitochondria-Derived Activator of Caspase (DIABLO) (C-Term) antibody (ABIN1030687)
Characteristics 16 amino acids near the carboxy terminus of mouse Smac.
Mouse
Application Notes Smac peptide is used for blocking the. activity of mSmac/DIABLO.
Restrictions For Research Use only
Format Liquid
Concentration 200 μg/mL
Buffer PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1 % bovine serum albumin and 0.02 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Expiry Date 12 months
Background publications Oda, Arakawa, Tanaka et al.: "p53AIP1, a potential mediator of p53-dependent apoptosis, and its regulation by Ser-46-phosphorylated p53." in: Cell, Vol. 102, Issue 6, pp. 849-62, 2000 (PubMed).

Verhagen, Ekert, Pakusch et al.: "Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins." in: Cell, Vol. 102, Issue 1, pp. 43-53, 2000 (PubMed).

Oda, Ohki, Murasawa et al.: "Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis." in: Science (New York, N.Y.), Vol. 288, Issue 5468, pp. 1053-8, 2000 (PubMed).