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anti-Primate AKT2 antibody for Immunofluorescence

Recommended AKT2 Antibody (supplied by: Log in to see )

Antigen
V-Akt Murine Thymoma Viral Oncogene Homolog 2 (AKT2) Antibodies
  • 2410016A19Rik
  • AKT2
  • akt2-a
  • AW554154
  • cb945
  • HIHGHH
  • PKB
  • PKBB
  • pkbb
  • PKBBETA
  • PKBbeta
  • pkbbeta
  • pkbss
  • prkbb
  • PRKBB
  • RAC-BETA
  • rac-beta
  • v-akt2
Reactivity
Human, Primate, Rat (Rattus)
386
123
98
30
28
25
23
21
21
19
19
19
19
1
1
Host
Mouse
301
69
12
10
3
2
Clonality
Monoclonal
Conjugate
This AKT2 antibody is un-conjugated
19
19
18
16
15
15
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunofluorescence (IF), Western Blotting (WB)
333
219
144
79
42
25
25
21
19
11
11
4
4
3
1
1
1
Supplier
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Catalog No. ABIN2869473
$ 464.29
Plus shipping costs $45.00

Top referenced anti-AKT2 antibody for Immunofluorescence

Similar anti-AKT2 Antibodies

Application / Reactivity Human Rat (Rattus) Primate
Western Blotting (WB) 327 Antibodies 86 Antibodies 1 Antibodies
Proximity Ligation Assay (PLA) 2 Antibodies
Luminex Assay (LMNX) 4 Antibodies
Immunoprecipitation (IP) 22 Antibodies 3 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 42 Antibodies 12 Antibodies
Immunohistochemistry (IHC) 137 Antibodies 44 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 4 Antibodies 2 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies 11 Antibodies
Immunofluorescence (IF) 81 Antibodies 32 Antibodies 1 Antibodies

General

Antigen V-Akt Murine Thymoma Viral Oncogene Homolog 2 (AKT2) Antibodies
Reactivity Human, Primate, Rat (Rattus)
(386), (123), (98), (30), (28), (25), (23), (21), (21), (19), (19), (19), (19), (1), (1)
Host Mouse
(301), (69), (12), (10), (3), (2)
Clonality
Monoclonal
Conjugate This AKT2 antibody is un-conjugated
(19), (19), (18), (16), (15), (15), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunofluorescence (IF), Western Blotting (WB)
(333), (219), (144), (79), (42), (25), (25), (21), (19), (11), (11), (4), (4), (3), (1), (1), (1)
Pubmed 2 references available
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Product Details anti-AKT2 Antibody

Target Details AKT2 Application Details Handling References for anti-AKT2 Antibody (ABIN2869473) Images
Specificity Purified recombinant fragment of human Akt2 expressed in E. Coli.
Purification This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Immunogen Purified recombinant fragment of human Akt2 expressed in E. Coli.
Isotype IgG2b

Target Details AKT2

Product Details anti-AKT2 Antibody Application Details Handling References for anti-AKT2 Antibody (ABIN2869473) Images back to top
Antigen
Alternative Name AKT2 (AKT2 Antibody Abstract)
Background Synonyms: Serine protease inhibitor J6, 47 kDa heat shock protein, Collagen-binding protein, Colligin, Serpin H1,Hsp47, Cbp1, Serpinh1
Molecular Weight 55769 DA
Gene ID 12406
NCBI Accession NP_001617
UniProt P31751
Research Area Ubiquitin-related antibodies, Phospho-specific antibodies, Signaling, Chromatin, Cell Structure
Pathways PI3K-Akt Signaling, RTK Signaling, AMPK Signaling, TLR Signaling

Application Details

Product Details anti-AKT2 Antibody Target Details AKT2 Handling References for anti-AKT2 Antibody (ABIN2869473) Images back to top
Application Notes Western Bloting: = 1:500 - 2000, Immunofluorescence: = 1:200 - 1000.
Comment

Background: Akt2 (also designated protein kinase B beta or v-akt murine thymoma viral oncogene homolog 2 ), with 481-amino acid protein (about 53kDa), belongs to the AKT serine/threonine protein kinase family, which also includes Akt1 and Akt3. They are involved in a wide variety of biological processes including cell proliferation, differentiation, apoptosis, tumorigenesis, as well as glycogen synthesis and glucose uptake. Among the members of AKT family, Akt2 is associated with the development of human cancers. Akt2 inhibits cisplatin-induced JNK/p38 and Bax activation through phosphorylation of ASK1 and thus, plays an important role in chemoresistance. Further, Akt2 plays a specific role in muscle differentiation.

Restrictions For Research Use only

Handling

Product Details anti-AKT2 Antibody Target Details AKT2 Application Details References for anti-AKT2 Antibody (ABIN2869473) Images back to top
Buffer PBS with 0.09% (w/v) sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Expiry Date 6 months

References for anti-AKT2 Antibody (ABIN2869473)

Product Details anti-AKT2 Antibody Target Details AKT2 Application Details Handling Images back to top
Background publications

Xu, Sakon, Nagano, Hiraoka, Yamamoto, Hayashi, Dono, Nakamori, Umeshita, Ito, Matsuura, Monden: "Akt2 expression correlates with prognosis of human hepatocellular carcinoma." in: Oncology reports, Vol. 11, Issue 1, pp. 25-32, 2003

Arboleda, Lyons, Kabbinavar, Bray, Snow, Ayala, Danino, Karlan, Slamon: "Overexpression of AKT2/protein kinase Bbeta leads to up-regulation of beta1 integrins, increased invasion, and metastasis of human breast and ovarian cancer cells." in: Cancer research, Vol. 63, Issue 1, pp. 196-206, 2003