anti-Human Cyclin D1 antibody for Flow Cytometry

Recommended Cyclin D1 Antibody (supplied by: Log in to see )

Antigen
Cyclin D1 (CCND1) Antibodies
  • ccnd1b
  • prad1
  • bcl1
  • d11s287e
  • u21b31
  • ccndbp1
  • ccnd1
  • ZHM
  • CCND1
  • BCL1
  • D11S287E
  • PRAD1
  • U21B31
  • AI327039
  • CycD1
  • Cyl-1
  • bcl-1
  • cD1
  • ccnd1a
  • cb161
  • cycd1
  • etID37810.7
  • fb52e01
  • fc45c08
  • fc83a12
  • id:ibd1198
  • wu:fb52e01
  • wu:fc45c08
  • wu:fc83a12
  • cyclin D1
  • Cyclin-D1-binding protein 1 homolog
  • cyclin Dx
  • zgc:162082
  • G1/S-specific cyclin-D1
  • ccnd1-b
  • ccnd1
  • ccndbp1
  • ccndx
  • zgc:162082
  • CCND1
  • Ccnd1
  • ccnd1-a
Reactivity
Human, Mouse (Murine)
488
243
237
44
21
20
19
16
16
14
5
4
4
4
4
3
3
2
2
2
2
2
1
1
1
1
1
1
Host
Mouse
326
203
19
4
Clonality
Monoclonal
Conjugate
This Cyclin D1 antibody is un-conjugated
26
23
15
10
5
5
4
4
4
4
4
4
4
4
4
4
4
4
3
3
3
2
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)
447
209
132
127
116
109
108
80
51
14
13
12
8
8
7
6
5
3
1
1
1
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Catalog No. ABIN1106871
$ 368.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
14.320307 ABIN4899040 CyTOF FACS WB Goat IgG AA 1-295 Log in to see Polyclonal 2
14.320307 ABIN671016 FACS IF (cc) IF (p) IHC (p) WB Rabbit IgG AA 70-120 Log in to see Polyclonal 15
14.320307 ABIN3026634 FACS IF IHC WB Mouse IgG2a, kappa Log in to see DCS-6
14.320307 ABIN3026632 FACS IF PE Mouse IgG2a, kappa Log in to see CCND1-809
14.320307 ABIN3025828 FACS IF IHC (p) WB Mouse IgG2a, kappa Log in to see CCND1-809
14.320307 ABIN3025831 FACS IF IHC (p) WB Mouse IgG2a, kappa Log in to see BCLD1-1
14.320307 ABIN3024574 FACS IF IHC WB Mouse IgG2a, kappa Log in to see SPM587
14.320307 ABIN5542302 ELISA FACS ICC IHC WB Mouse IgG1 AA 167-295 Log in to see 3B6G3
1 ABIN967430 FACS IP IHC WB Mouse IgG1 full length Log in to see G124-326 5
1 ABIN967431 FACS IP IHC WB Mouse IgG1 full length Log in to see G124-326 5
1 ABIN119000 EIA FACS IHC (fro) IHC (p) IP WB Mouse IgG1 Log in to see CD1-1
1 ABIN892917 FACS IF (cc) IF (p) Alexa Fluor 555 Rabbit IgG AA 70-120 Log in to see Polyclonal 1
1 ABIN2471067 ICC FACS IP IHC ELISA WB Mouse IgG1 Log in to see CD1-1
1 ABIN574432 ICC IHC (fro) FACS IHC (p) IP ELISA WB Mouse IgG1 Log in to see CD1-1
1 ABIN4880607 ELISA FACS ICC IHC WB Mouse IgG1 AA 167-295 Log in to see 3B6G3
1 ABIN1723570 ICC IHC (fro) FACS IHC (p) IP ELISA WB Mouse IgG1 Log in to see CD1-1
1 ABIN302101 ELISA FACS ICC IHC (f) IHC (p) IP WB Mouse IgG1 Log in to see CD1-1 2
1 ABIN199058 FACS IF IHC WB FITC Mouse IgG2a, kappa Log in to see
1 ABIN255827 FACS IHC (fro) IHC (p) IP IHC ELISA WB Mouse IgG1 Log in to see CD1-1
1 ABIN1824080 FACS IP WB Mouse IgG2a Log in to see DCS-6

General

Antigen Cyclin D1 (CCND1) Antibodies
Reactivity Human, Mouse (Murine)
(488), (243), (237), (44), (21), (20), (19), (16), (16), (14), (5), (4), (4), (4), (4), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Host Mouse
(326), (203), (19), (4)
Clonality (Clone)
Monoclonal   ( )
Conjugate This Cyclin D1 antibody is un-conjugated
(26), (23), (15), (10), (5), (5), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (3), (3), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)
(447), (209), (132), (127), (116), (109), (108), (80), (51), (14), (13), (12), (8), (8), (7), (6), (5), (3), (1), (1), (1)
Pubmed 3 references available
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Product Details anti-Cyclin D1 Antibody

Target Details Cyclin D1 Application Details Handling ProductDetails: References for anti-Cyclin D1 antibody (ABIN1106871) Images
Specificity This antibody reacts with human Cyclin D1 (36 kDa). This clone 5D4 recognizes human Cyclin D1, D2 and mouse Cyclin D1, D2, but not human and mouse Cyclin D3.
Cross-Reactivity (Details) Species reactivity (tested):Human, mouse
Purification Protein A agarose
Immunogen Recombinant human PRAD1/Cyclin D1
Clone 5D4
Isotype IgG2a

Target Details Cyclin D1

Product Details anti-Cyclin D1 Antibody Application Details Handling ProductDetails: References for anti-Cyclin D1 antibody (ABIN1106871) Images back to top
Antigen
Alternative Name Cyclin D1 (CCND1 Antibody Abstract)
Background Cyclin D1, also known as Bcl-1, CCND1, or PRAD-1, is a 36 kDa nuclear protein that plays a key regulatory role during the G1 phase of the cell cycle by regulating the activity of Cdk proteins. Cyclin D1 forms a complex with Cdk4, then binds to and phosphorylates Rb protein, triggering cells to progress from G0/G1 to S and thus driving cellular proliferation. Cyclin D1 protein overexpression is found in the majority of human breast cancers and is usually linked with poor prognosis. Overexpression of cyclin D1 is a well-established criterion for the diagnosis of Mantle Cell Lymphoma, and also has been used to distinguish malignant breast carcinomas from premalignant breast lesions.Synonyms: BCL-1 oncogene, BCL1, CCND1, Cyclin-D1, G1/S-specific cyclin-D1, PRAD-1 oncogene, PRAD1
Gene ID 595
NCBI Accession NP_444284
UniProt P24385
Research Area Cancer, Cell Cycle
Pathways PI3K-Akt Signaling, Cell Division Cycle, Mitotic G1-G1/S Phases, ER-Nucleus Signaling

Application Details

Product Details anti-Cyclin D1 Antibody Target Details Cyclin D1 Handling ProductDetails: References for anti-Cyclin D1 antibody (ABIN1106871) Images back to top
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only

Handling

Product Details anti-Cyclin D1 Antibody Target Details Cyclin D1 Application Details ProductDetails: References for anti-Cyclin D1 antibody (ABIN1106871) Images back to top
Concentration 1.0 mg/mL
Buffer PBS containing 50 % glycerol, pH 7.2
Preservative Azide free
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Store (in aliquots) at -20 °C.

ProductDetails: References for anti-Cyclin D1 antibody (ABIN1106871)

Product Details anti-Cyclin D1 Antibody Target Details Cyclin D1 Application Details Handling Images back to top
Background publications

Zou, Peng, Zhou, Wen, Wang, Tsai, Hung: "Systemic tumor suppression by the proapoptotic gene bik." in: Cancer research, Vol. 62, Issue 1, pp. 8-12, 2002

Bowen: "Haemophilia A and haemophilia B: molecular insights." in: Molecular pathology : MP, Vol. 55, Issue 1, pp. 1-18, 2002

Inagaki, Chan, Ng, Okabe, Yoshino, Okamoto, Ogawa, Matsushita, Yokose, Matsuno, Nakamura, Nagasaka, Ueda, Eimoto, Nakamura: "Primary thymic extranodal marginal-zone B-cell lymphoma of mucosa-associated lymphoid tissue type exhibits distinctive clinicopathological and molecular features." in: The American journal of pathology, Vol. 160, Issue 4, pp. 1435-43, 2002

Images

Product Details anti-Cyclin D1 Antibody Target Details Cyclin D1 Application Details Handling ProductDetails: References for anti-Cyclin D1 antibody (ABIN1106871) back to top
Supplier Images
Flow Cytometry (FACS) image for anti-Cyclin D1 (CCND1) antibody (ABIN1106871) anti-Cyclin D1 (CCND1) antibody
Immunohistochemistry (IHC) image for anti-Cyclin D1 (CCND1) antibody (ABIN1106871) anti-Cyclin D1 (CCND1) antibody (Image 2)
Western Blotting (WB) image for anti-Cyclin D1 (CCND1) antibody (ABIN1106871) anti-Cyclin D1 (CCND1) antibody (Image 3)
Western Blotting (WB) image for anti-Cyclin D1 (CCND1) antibody (ABIN1106871) anti-Cyclin D1 (CCND1) antibody (Image 4)