anti-Mouse (Murine) Cyclin D1 antibody for Immunofluorescence (Paraffin-embedded Sections)

Recommended Cyclin D1 Antibody (supplied by: Log in to see )

Antigen
Cyclin D1 (CCND1) Antibodies
  • ccnd1b
  • prad1
  • bcl1
  • d11s287e
  • u21b31
  • ccndbp1
  • ccnd1
  • ZHM
  • CCND1
  • BCL1
  • D11S287E
  • PRAD1
  • U21B31
  • AI327039
  • CycD1
  • Cyl-1
  • bcl-1
  • cD1
  • ccnd1a
  • cb161
  • cycd1
  • etID37810.7
  • fb52e01
  • fc45c08
  • fc83a12
  • id:ibd1198
  • wu:fb52e01
  • wu:fc45c08
  • wu:fc83a12
  • cyclin D1
  • Cyclin-D1-binding protein 1 homolog
  • cyclin Dx
  • zgc:162082
  • G1/S-specific cyclin-D1
  • ccnd1-b
  • ccnd1
  • ccndbp1
  • ccndx
  • zgc:162082
  • CCND1
  • Ccnd1
  • ccnd1-a
Epitope
AA 70-120
81
24
21
15
14
12
12
10
9
8
8
6
6
5
5
5
5
5
5
5
4
4
4
3
3
3
3
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Reactivity
Goat, Human, Mouse (Murine), Rat (Rattus)
476
244
237
44
21
20
19
16
15
14
5
4
4
4
4
3
3
2
2
2
2
2
1
1
1
1
1
1
Host
Rabbit
322
194
19
4
Clonality
Polyclonal
Conjugate
This Cyclin D1 antibody is un-conjugated
26
23
12
10
5
5
4
4
4
4
4
4
4
4
4
4
4
4
3
3
3
2
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
438
204
127
125
110
109
105
79
50
13
12
12
8
8
7
6
4
3
1
1
1
Options
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Catalog No. ABIN671016
$ 307.45
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN892917 FACS IF (cc) IF (p) Alexa Fluor 555 Rabbit IgG AA 70-120 Log in to see Polyclonal 1
1 ABIN2809057 FACS IF (cc) IF (p) Alexa Fluor 594 Rabbit IgG AA 70-120 Log in to see Polyclonal
1 ABIN892920 FACS IF (cc) IF (p) Alexa Fluor 647 Rabbit IgG AA 70-120 Log in to see Polyclonal
1 ABIN892918 FACS IF (cc) IF (p) Alexa Fluor 350 Rabbit IgG AA 70-120 Log in to see Polyclonal
1 ABIN892919 FACS IF (cc) IF (p) Alexa Fluor 488 Rabbit IgG AA 70-120 Log in to see Polyclonal
1 ABIN671020 FACS IF (cc) IF (p) Cy5 Rabbit IgG AA 70-120 Log in to see Polyclonal
1 ABIN671019 FACS IF (cc) IF (p) Cy3 Rabbit IgG AA 70-120 Log in to see Polyclonal
1 ABIN671022 FACS IF (cc) IF (p) Cy7 Rabbit IgG AA 70-120 Log in to see Polyclonal
1 ABIN671021 FACS IF (cc) IF (p) Cy5.5 Rabbit IgG AA 70-120 Log in to see Polyclonal
1 ABIN671023 FACS IF (cc) IF (p) FITC Rabbit IgG AA 70-120 Log in to see Polyclonal
1 ABIN5000805 FACS IF (cc) IF (p) Alexa Fluor 750 Rabbit IgG AA 70-120 Log in to see Polyclonal
1 ABIN5000804 FACS IF (cc) IF (p) Alexa Fluor 680 Rabbit IgG AA 70-120 Log in to see Polyclonal

Top referenced anti-Cyclin D1 antibody for Immunofluorescence (Paraffin-embedded Sections)

Similar anti-Cyclin D1 Antibodies

Application / Reactivity Rat (Rattus)
Blocking Reagent (BR) 1 Antibodies
Cytometry by Time of Flight (CyTOF) 2 Antibodies
ELISA 87 Antibodies
Enzyme Immunoassay (EIA) 2 Antibodies
Flow Cytometry (FACS) 67 Antibodies
Functional Studies (Func) 8 Antibodies
Immunochromatography (IC) 1 Antibodies
Immunocytochemistry (ICC) 48 Antibodies
Immunofluorescence (IF) 54 Antibodies
Immunofluorescence (Cultured Cells) (IF (cc)) 13 Antibodies
Immunofluorescence (fixed cells) (IF/ICC) 5 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 13 Antibodies
Immunohistochemistry (IHC) 56 Antibodies
Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) 4 Antibodies
Immunohistochemistry (Frozen Sections) (IHC (fro)) 37 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 60 Antibodies
Immunoprecipitation (IP) 75 Antibodies
Intracellular Staining (ICS) 1 Antibodies
Western Blotting (WB) 190 Antibodies

General

Antigen Cyclin D1 (CCND1) Antibodies
Epitope AA 70-120
(81), (24), (21), (15), (14), (12), (12), (10), (9), (8), (8), (6), (6), (5), (5), (5), (5), (5), (5), (5), (4), (4), (4), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Goat, Human, Mouse (Murine), Rat (Rattus)
(476), (244), (237), (44), (21), (20), (19), (16), (15), (14), (5), (4), (4), (4), (4), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Host Rabbit
(322), (194), (19), (4)
Clonality
Polyclonal
Conjugate This Cyclin D1 antibody is un-conjugated
(26), (23), (12), (10), (5), (5), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (3), (3), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(438), (204), (127), (125), (110), (109), (105), (79), (50), (13), (12), (12), (8), (8), (7), (6), (4), (3), (1), (1), (1)
Pubmed 15 references available
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Product Details anti-Cyclin D1 Antibody

Target Details Cyclin D1 Application Details Handling ProductDetails: References for anti-Cyclin D1 antibody (ABIN671016) Images
Purification Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from mouse Cyclin D1
Isotype IgG

Target Details Cyclin D1

Product Details anti-Cyclin D1 Antibody Application Details Handling ProductDetails: References for anti-Cyclin D1 antibody (ABIN671016) Images back to top
Antigen
Alternative Name Cyclin D1 (CCND1 Antibody Abstract)
Background

Regulatory component of the cyclin D1-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G(1)/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase. Hypophosphorylates RB1 in early G(1) phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. Also substrate for SMAD3, phosphorylating SMAD3 in a cell-cycle-dependent manner and repressing its transcriptional activity. Component of the ternary complex, cyclin D1/CDK4/CDKN1B, required for nuclear translocation and activity of the cyclin D-CDK4 complex. Exhibits transcriptional corepressor activity with INSM1 on the NEUROD1 and INS promoters in a cell cycle-independent manner (By similarity).

Subcellular location: Cytoplasm, Nucleus


Synonyms: cD1, CycD1, Cyl-1, PRAD1, bcl-1, AI32739, G1/S-specific cyclin-D1, Ccnd1
Gene ID 12443
UniProt P25322
Research Area Cancer, Cell Cycle
Pathways PI3K-Akt Signaling, Cell Division Cycle, Mitotic G1-G1/S Phases, ER-Nucleus Signaling

Application Details

Product Details anti-Cyclin D1 Antibody Target Details Cyclin D1 Handling ProductDetails: References for anti-Cyclin D1 antibody (ABIN671016) Images back to top
Application Notes WB(1:100-1000), FCM(1:20-100), IHC-P(1:100-500), IF(IHC-P)(1:50-200), IF(ICC)(1:50-200)
Restrictions For Research Use only

Handling

Product Details anti-Cyclin D1 Antibody Target Details Cyclin D1 Application Details ProductDetails: References for anti-Cyclin D1 antibody (ABIN671016) Images back to top
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months

ProductDetails: References for anti-Cyclin D1 antibody (ABIN671016)

Product Details anti-Cyclin D1 Antibody Target Details Cyclin D1 Application Details Handling Images back to top
Product cited in:

Jiang, Xie, Cai, Ren, Ma: "Effects of hepatitis C virus core protein and nonstructural protein 4B on the Wnt/β-catenin pathway." in: BMC microbiology, Vol. 17, Issue 1, pp. 124, 2017 Method employed by authors: Western Blotting (WB) (Sample species: Human).

Wang, Cao, Sun, Dai, Fang, Li, Yan, Mao, Zhang: "Total flavonoid aglycones extract in Radix scutellariae inhibits lung carcinoma and lung metastasis by affecting cell cycle and DNA synthesis." in: Journal of ethnopharmacology, Vol. 194, pp. 269-279, 2016

Zhang, Pan, Xu, Niu, Ma, Xu: "Interleukin 18 augments growth ability via NF-?B and p38/ATF2 pathways by targeting cyclin B1, cyclin B2, cyclin A2, and Bcl-2 in BRL-3A rat liver cells." in: Gene, Vol. 563, Issue 1, pp. 45-51, 2015

Wang, Yang, Liu, Huang, Wang, Chen, Chen: "RBP-J-interacting and tubulin-associated protein induces apoptosis and cell cycle arrest in human hepatocellular carcinoma by activating the p53-Fbxw7 pathway." in: Biochemical and biophysical research communications, Vol. 454, Issue 1, pp. 71-7, 2015

Yang, Wang, Hui, Li, Jiang: "SOX 1, contrary to SOX 2, suppresses proliferation, migration, and invasion in human laryngeal squamous cell carcinoma by inhibiting the Wnt/?-catenin pathway." in: Tumour biology, 2015

Shi, Lu, Zhou, Tan, He, Ding, Tian, Wang, Wang: "Long non-coding RNA Loc554202 regulates proliferation and migration in breast cancer cells." in: Biochemical and biophysical research communications, Vol. 446, Issue 2, pp. 448-53, 2014

Ye, Li, Li, Yang, Niu, Wang: "Anti-tumor activity and relative mechanism of ethanolic extract of Marsdenia tenacissima (Asclepiadaceae) against human hematologic neoplasm in vitro and in vivo." in: Journal of ethnopharmacology, Vol. 153, Issue 1, pp. 258-67, 2014

Lin, Wang, Wang, Fang, Zhang, Yang, Guo, Lin, Zhang, Wang: "Lithocarpus polystachyus REHD leaf aqueous extract inhibits human breast cancer growth in vitro and in vivo." in: Nutrition and cancer, Vol. 66, Issue 4, pp. 613-24, 2014

He, Xiang, Zong, Yan, Yu, Liu, Zou, Yang: "CDK2-AP1 inhibits growth of breast cancer cells by regulating cell cycle and increasing docetaxel sensitivity in vivo and in vitro." in: Cancer cell international, Vol. 14, Issue 1, pp. 130, 2014

Souza, Silva, Calloway, Kucuk, Rossi, McLemore: "Genistein protects hematopoietic stem cells against G-CSF-induced DNA damage." in: Cancer prevention research (Philadelphia, Pa.), Vol. 7, Issue 5, pp. 534-44, 2014

Li, Yu, Liu, Zhu, He, Peng, Hua: "miR-34c works downstream of p53 leading to dairy goat male germline stem-cell (mGSCs) apoptosis." in: Cell proliferation, Vol. 46, Issue 2, pp. 223-31, 2013 (1:1000).

Teng, Chang, Wang, Lu, Wu, Yang, Chiu, Yang, Hsu, Ho: "Phospholipid-functionalized mesoporous silica nanocarriers for selective photodynamic therapy of cancer." in: Biomaterials, Vol. 34, Issue 30, pp. 7462-70, 2013

Wang, Wu, Gao, Chen, Gu, Ding, Guo: "Elevated toll-like receptor 3 inhibits pancreatic ?-cell proliferation through G1 phase cell cycle arrest." in: Molecular and cellular endocrinology, Vol. 377, Issue 1-2, pp. 112-22, 2013

Zhang, Tan, Wang, Chen, Quan, Xian, Zhang, He, Zhang: "Musashi2 modulates K562 leukemic cell proliferation and apoptosis involving the MAPK pathway." in: Experimental cell research, Vol. 320, Issue 1, pp. 119-27, 2013

Chen, Shi, Liu, Fang, Zhang, Zhao: "Targeting SPARC by lentivirus-mediated RNA interference inhibits cervical cancer cell growth and metastasis." in: BMC cancer, Vol. 12, pp. 464, 2012 (1:1000).

Images

Product Details anti-Cyclin D1 Antibody Target Details Cyclin D1 Application Details Handling ProductDetails: References for anti-Cyclin D1 antibody (ABIN671016) back to top
Supplier Images
Immunohistochemistry (IHC) image for anti-Cyclin D1 antibody (CCND1) (AA 70-120) (ABIN671016) Formalin-fixed and paraffin embedded human placenta tissue labeled with Anti-Cyclin D...
Immunohistochemistry (IHC) image for anti-Cyclin D1 antibody (CCND1) (AA 70-120) (ABIN671016) Formalin-fixed and paraffin embedded human placenta tissue labeled with Anti-Cyclin D...
Western Blotting (WB) image for anti-Cyclin D1 antibody (CCND1) (AA 70-120) (ABIN671016) A549 cells probed with Anti-Cyclin D1 Polyclonal Antibody at 1:5000 90min in 37˚C.
Flow Cytometry (FACS) image for anti-Cyclin D1 antibody (CCND1) (AA 70-120) (ABIN671016) RSC96 cells probed with Cyclin D1 Polyclonal Antibody, Unconjugated at 1:100 for 30 ...
Immunofluorescence (Cultured Cells) (IF (cc)) image for anti-Cyclin D1 antibody (CCND1) (AA 70-120) (ABIN671016) Image provided by One World Lab validation program. MCF-7 cells probed with Rabbit An...
Immunofluorescence (Cultured Cells) (IF (cc)) image for anti-Cyclin D1 antibody (CCND1) (AA 70-120) (ABIN671016) Image provided by One World Lab validation program. HEK293 cells probed with Rabbit A...