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anti-Human PIK3CG antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended PIK3CG Antibody (supplied by: Log in to see )

Antigen
Phosphoinositide-3-Kinase, Catalytic, gamma Polypeptide (PIK3CG) Antibodies
  • 5830428L06Rik
  • p110gamma
  • p120-PI3K
  • PI3CG
  • pi3k
  • Pi3k
  • PI3K
  • PI3Kgamma
  • PIK3
  • wu:fb15d07
  • zgc:77033
Epitope
AA 1073-1102, C-Term
28
23
13
11
7
7
2
2
2
1
1
1
1
1
1
Reactivity
Human
156
19
12
3
2
1
1
Host
Rabbit
114
30
12
1
Clonality
Polyclonal
Conjugate
This PIK3CG antibody is un-conjugated
10
10
10
10
10
10
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
122
91
42
18
18
16
5
3
2
2
1
Supplier
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Catalog No. ABIN360452
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0008982679 ABIN360713 EIA IHC (p) WB Rabbit Ig Middle Region Log in to see Polyclonal 5
0.0008982679 ABIN360712 EIA IHC (p) WB Rabbit Ig C-Term Log in to see Polyclonal 5
0.0008982679 ABIN1500203 IF IHC (p) WB Mouse IgG2a Log in to see 6H5
0.0008982679 ABIN1500205 IF IHC (p) WB Mouse IgG2a Log in to see 4G10
0.0008982679 ABIN1500206 IF IHC (p) WB Mouse IgG2a Log in to see 6D1
0.0008982679 ABIN1500207 IHC (p) WB Mouse IgG2a Log in to see 2B1
0.0008982679 ABIN1500204 IF IHC (p) WB Mouse IgG1 Log in to see 6G5
0.0008982679 ABIN1500209 IHC (p) WB Mouse IgG1 Log in to see 4B1
0.0008982679 ABIN1500202 IF IHC (p) WB Mouse IgG1 Log in to see 4D3
0.0008982679 ABIN2855878 IHC (p) WB Rabbit IgG C-Term Log in to see Polyclonal
0.0008982679 ABIN1500208 IHC (p) WB Mouse IgG2a Log in to see 6C6
0.0008982679 ABIN1804630 IHC (p) WB Rabbit IgG Log in to see Polyclonal
0.0008982679 ABIN2583753 IHC (p) Mouse IgG2a Log in to see 1A9
0.0008982679 ABIN2583754 IHC (p) Mouse IgG2b Log in to see 4B9
0.0008982679 ABIN1805251 IHC (p) WB Rabbit C-Term Log in to see Polyclonal
0.0008982679 ABIN1805252 IHC (p) WB Rabbit Internal Region Log in to see Polyclonal
0.0008982679 ABIN1841509 IHC (p) WB Rabbit C-Term Log in to see Polyclonal
0.0008982679 ABIN2963810 IHC (p) WB Rabbit IgG Log in to see Polyclonal

Similar anti-PIK3CG Antibodies

Application / Reactivity Human
Dot Blot (DB) 18 Antibodies
ELISA 92 Antibodies
ELISA (Capture) 1 Antibodies
Enzyme Immunoassay (EIA) 6 Antibodies
Immunocytochemistry (ICC) 2 Antibodies
Immunofluorescence (IF) 16 Antibodies
Immunohistochemistry (IHC) 42 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 19 Antibodies
Immunoprecipitation (IP) 3 Antibodies
Proximity Ligation Assay (PLA) 2 Antibodies
Western Blotting (WB) 124 Antibodies

General

Antigen Phosphoinositide-3-Kinase, Catalytic, gamma Polypeptide (PIK3CG) Antibodies
Epitope AA 1073-1102, C-Term
(28), (23), (13), (11), (7), (7), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Reactivity Human
(156), (19), (12), (3), (2), (1), (1)
Host Rabbit
(114), (30), (12), (1)
Clonality
Polyclonal
Conjugate This PIK3CG antibody is un-conjugated
(10), (10), (10), (10), (10), (10)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(122), (91), (42), (18), (18), (16), (5), (3), (2), (2), (1)
Pubmed 5 references available
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Product Details anti-PIK3CG Antibody

Target Details PIK3CG Application Details Handling References for anti-PIK3CG Antibody (ABIN360452) Images
Specificity This antibody reacts to PI3KCG.
Purification Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
Immunogen This PI3KCG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1073~1102 amino acids from the C-terminal region of Human PI3KCG.
Isotype Ig

Target Details PIK3CG

Product Details anti-PIK3CG Antibody Application Details Handling References for anti-PIK3CG Antibody (ABIN360452) Images back to top
Antigen
Alternative Name PIK3CG (PIK3CG Antibody Abstract)
Background PI3KCG belongs to the pi3/pi4-kinase family of proteins. This protein is an enzyme that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring. It is an important modulator of extracellular signals, including those elicited by E-cadherin-mediated cell-cell adhesion, which plays an important role in maintenance of the structural and functional integrity of epithelia. In addition to its role in promoting assembly of adherens junctions, the protein is thought to play a pivotal role in the regulation of cytotoxicity in NK cells.Synonyms: 5-bisphosphate 3-kinase catalytic subunit gamma isoform, PI3-kinase subunit gamma, PI3K-gamma, Phosphatidylinositol-4, PtdIns-3-kinase subunit p110-gamma, p120-PI3K
Gene ID 5294, 9606
UniProt P48736
Research Area Kinases/Phosphatases, Signaling, Cancer
Pathways PI3K-Akt Signaling, RTK Signaling, AMPK Signaling, TLR Signaling

Application Details

Product Details anti-PIK3CG Antibody Target Details PIK3CG Handling References for anti-PIK3CG Antibody (ABIN360452) Images back to top
Application Notes ELISA: 1/1,000. Immunohistochemistry: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-PIK3CG Antibody Target Details PIK3CG Application Details References for anti-PIK3CG Antibody (ABIN360452) Images back to top
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

References for anti-PIK3CG Antibody (ABIN360452)

Product Details anti-PIK3CG Antibody Target Details PIK3CG Application Details Handling Images back to top
Background publications

Reséndiz, Feng, Ji, Francis, Berndt, Kroll: "Purinergic P2Y12 receptor blockade inhibits shear-induced platelet phosphatidylinositol 3-kinase activation." in: Molecular pharmacology, Vol. 63, Issue 3, pp. 639-45, 2003

François, Klotman: "Phosphatidylinositol 3-kinase regulates human immunodeficiency virus type 1 replication following viral entry in primary CD4+ T lymphocytes and macrophages." in: Journal of virology, Vol. 77, Issue 4, pp. 2539-49, 2003

Chandrasekar, Mohanam, Gujrati, Olivero, Dinh, Rao: "Downregulation of uPA inhibits migration and PI3k/Akt signaling in glioblastoma cells." in: Oncogene, Vol. 22, Issue 3, pp. 392-400, 2003

Ishibashi, Yoshimura, Nishikawa, Claus, Laudanna, Relman: "Role of phosphatidylinositol 3-kinase in the binding of Bordetella pertussis to human monocytes." in: Cellular microbiology, Vol. 4, Issue 12, pp. 825-33, 2002

Semba, Itoh, Ito, Youssef, Harada, Moriya, Kimura, Yamakawa: "Down-regulation of PIK3CG, a catalytic subunit of phosphatidylinositol 3-OH kinase, by CpG hypermethylation in human colorectal carcinoma." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 8, Issue 12, pp. 3824-31, 2002

Images

Product Details anti-PIK3CG Antibody Target Details PIK3CG Application Details Handling References for anti-PIK3CG Antibody (ABIN360452) back to top
Supplier Images
 image for anti-PIK3CG antibody (Phosphoinositide-3-Kinase, Catalytic, gamma Polypeptide) (AA 1073-1102) (ABIN360452) anti-Phosphoinositide-3-Kinase, Catalytic, gamma Polypeptide (PIK3CG) (AA 1073-1102), (C-Term) antibody
 image for anti-PIK3CG antibody (Phosphoinositide-3-Kinase, Catalytic, gamma Polypeptide) (AA 1073-1102) (ABIN360452) anti-Phosphoinositide-3-Kinase, Catalytic, gamma Polypeptide (PIK3CG) (AA 1073-1102), (C-Term) antibody (Image 2)