CD200R1 Protein (AA 27-266) (His tag)
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- Target See all CD200R1 Proteins
- CD200R1 (CD200 Receptor 1 (CD200R1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 27-266
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Origin
- Human
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Source
- Human Cells
- Purification tag / Conjugate
- This CD200R1 protein is labelled with His tag.
- Purpose
- Recombinant Human CD200 Receptor 1/CD200R1 (C-6His)
- Sequence
- AAQPNNSLML QTSKENHALA SSSLCMDEKQ ITQNYSKVLA EVNTSWPVKM ATNAVLCCPP IALRNLIIIT WEIILRGQPS CTKAYKKETN ETKETNCTDE RITWVSRPDQ NSDLQIRTVA ITHDGYYRCI MVTPDGNFHR GYHLQVLVTP EVTLFQNRNR TAVCKAVAGK PAAHISWIPE GDCATKQEYW SNGTVTVKST CHWEVHNVST VTCHVSHLTG NKSLYIELLP VPGAKKSAKL VDHHHHHH
- Characteristics
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Recombinant Human CD200 Receptor 1/CD200R1 (C-6His)
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product CD200R1 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.
- Handling Advice
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- Storage
- 4 °C/-20 °C/-80 °C
- Storage Comment
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Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- CD200R1 (CD200 Receptor 1 (CD200R1))
- Alternative Name
- CD200 R1 (CD200R1 Products)
- Synonyms
- CD200R Protein, HCRTR2 Protein, MOX2R Protein, OX2R Protein, Mox2r Protein, CD200R1 Protein, CD200R2 Protein, CD200R-B1V1 Protein, CD200R1A Protein, CD200 receptor 1 Protein, cell surface glycoprotein CD200 receptor 1 Protein, CD200 receptor 1-like Protein, CD200R1 Protein, Cd200r1 Protein, LOC487977 Protein, CD200R1L Protein
- Background
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Recombinant Human CD200 R1 is produced with our mammalian expression system in human cells. The target protein is expressed with sequence (Met29-Leu325) of Human CD200 R1 fused with a polyhistidine tag at the C-terminus.
Cell surface glycoprotein CD200 Receptor 1 (CD200R1) is the receptor for the CD200 (OX-2) membrane glycoprotein. CD200R1 contains one C2- type Ig-like domain and one V-type Ig-like domain within its extracellular domain and a PTB-signaling motif in cytoplasmic domain. CD200R1 and CD200 associate via their respective N-terminal Ig-like domains. CD200R1 is restricted primarily to mast cells, basophils, macrophages, and dendritic cells. It propagates inhibitory signals despite its lacking a cytoplasmic ITIM (immunoreceptor tyrosinebased inhibitory motif). The receptor-substrate interaction may function as a myeloid downregulatory signal. - Molecular Weight
- 25.22 kDa
- UniProt
- Q8TD46
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