CD200R1 Protein (AA 25-267) (His tag)

Catalog No. ABIN7274101

Product Details

Target: CD200R1 (CD200 Receptor 1 (CD200R1))

Protein Type: Recombinant

Protein Characteristics: AA 25-267

Origin: Cynomolgus

Source: HEK-293 Cells

Purification tag / Conjugate: This CD200R1 protein is labelled with His tag.

Purpose: Cynomolgus CD200 R1/CRTR2 Protein

Sequence: Glu25-Leu267

Characteristics: Recombinant Cynomolgus CD200 R1/CRTR2 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Glu25-Leu267.

Purity: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Sterility: 0.22 μm filtered

Endotoxin Level: Less than 1EU per μg by the LAL method.

Biological Activity Comment: The affinity constant of 35.84 nM as determined in SPR assay (Biacore T200). See testing image for detail.

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Storage: -20 °C,-80 °C

Storage Comment: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Expiry Date: 12 months

Target Details

Target: CD200R1 (CD200 Receptor 1 (CD200R1))

Alternative Name: CD200 R1 (CD200R1 Products)

Synonyms: CD200R Protein, HCRTR2 Protein, MOX2R Protein, OX2R Protein, Mox2r Protein, CD200R1 Protein, CD200R2 Protein, CD200R-B1V1 Protein, CD200R1A Protein, CD200 receptor 1 Protein, cell surface glycoprotein CD200 receptor 1 Protein, CD200 receptor 1-like Protein, CD200R1 Protein, Cd200r1 Protein, LOC487977 Protein, CD200R1L Protein

Background: CD200Fc, a chimeric molecule including the extracellular domain of CD200 and a murine IgG2a Fc region, regulates immune responses following engagement of a cell surface receptor, CD200R, expressed on cells of the myeloid and T cell lineage. A recent report focused attention on a family of CD200Rs, but concluded that only one member used CD200 as its ligand.

Molecular Weight: 28.09 kDa. Due to glycosylation, the protein migrates to 67-77 kDa based on Tris-Bis PAGE result.

NCBI Accession: XP_005548207