TSTA3 Protein (AA 1-321) (His tag)
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- Target See all TSTA3 Proteins
- TSTA3 (Tissue Specific Transplantation Antigen P35B (TSTA3))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-321
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This TSTA3 protein is labelled with His tag.
- Purpose
- Recombinant Human GDP-L-Fucose Synthase/TSTA3/SDR4E1 (C-6His)
- Sequence
- MGEPQGSMRI LVTGGSGLVG KAIQKVVADG AGLPGEDWVF VSSKDADLTD TAQTRALFEK VQPTHVIHLA AMVGGLFRNI KYNLDFWRKN VHMNDNVLHS AFEVGARKVV SCLSTCIFPD KTTYPIDETM IHNGPPHNSN FGYSYAKRMI DVQNRAYFQQ YGCTFTAVIP TNVFGPHDNF NIEDGHVLPG LIHKVHLAKS SGSALTVWGT GNPRRQFIYS LDLAQLFIWV LREYNEVEPI ILSVGEEDEV SIKEAAEAVV EAMDFHGEVT FDTTKSDGQF KKTASNSKLR TYLPDFRFTP FKQAVKETCA WFTDNYEQAR KLEHHHHHH
- Characteristics
- Recombinant Human GDP-L-Fucose Synthase is produced by our E.coli expression system. The target protein is expressed with sequence (Met1-Lys321) of Human TSTA3 fused with a 6His tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product TSTA3 Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Reconstitution
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM Tris, 150 mM NaCl, pH 8.0.
- Handling Advice
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- Storage
- -80 °C
- Storage Comment
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Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles. - Expiry Date
- 6 months
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- Target
- TSTA3 (Tissue Specific Transplantation Antigen P35B (TSTA3))
- Alternative Name
- TSTA3 (TSTA3 Products)
- Synonyms
- FX Protein, P35B Protein, SDR4E1 Protein, AI256181 Protein, Tstap35b Protein, p35b Protein, sdr4e1 Protein, TSTA3 Protein, zgc:101805 Protein, si:dkey-235d18none Protein, Fx Protein, tissue specific transplantation antigen P35B Protein, tissue specific transplantation antigen P35B L homeolog Protein, TSTA3 Protein, Tsta3 Protein, tsta3 Protein, tsta3.L Protein
- Sub Type
- Fusionprotein
- Background
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GDP-L-Fucose Synthase is a NADP(H)-binding protein. It catalyzes the two-step epimerase and the reductase reactions in GDP-D-mannose metabolism, converting GDP-4-keto-6-D-dexoymannose to GDP-L-fucose. GDP-L-Fucose is the substrate of several fucosyltransferase, involving the expression of mamy glycoconjugates, including blood group ABH antigens and development adhesion antigens. Mutations in the TSTA3 gene may cause leukocyte adhesion deficiency type II.
Alternative Names: GDP-L-Fucose Synthase, GDP-4-Keto-6-Deoxy-D-Mannose-3,5-Epimerase-4-Reductase, Protein FX, Red Cell NADP(H)-Binding Protein, Short-Chain Dehydrogenase/Reductase Family 4E Member 1, TSTA3, SDR4E1 - Molecular Weight
- 36.96 kDa
- UniProt
- Q13630
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