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TSTA3 Protein (His tag)

TSTA3 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7318528
  • Target See all TSTA3 Proteins
    TSTA3 (Tissue Specific Transplantation Antigen P35B (TSTA3))
    Protein Type
    Recombinant
    Origin
    • 5
    • 1
    • 1
    • 1
    Human
    Source
    • 3
    • 2
    • 2
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This TSTA3 protein is labelled with His tag.
    Purpose
    Recombinant Human TSTA3/SDR4E1 Protein (His Tag)
    Sequence
    Met 1-Lys321
    Characteristics
    Recombinant Human GDP-L-Fucose Synthase is produced by our E.coli expression system and the target gene encoding Met1-Lys321 is expressed with a 6His tag at the C-terminus.
    Purity
    > 95 % as determined by reducing SDS-PAGE.
    Endotoxin Level
    < 1.0 EU per μg as determined by the LAL method.
    Top Product
    Discover our top product TSTA3 Protein
  • Restrictions
    For Research Use only
  • Format
    Frozen, Liquid
    Buffer
    Supplied as a 0.2 μm filtered solution of 20 mM Tris, 150 mM NaCl, pH 8.0.
    Storage
    -20 °C
    Storage Comment
    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Target
    TSTA3 (Tissue Specific Transplantation Antigen P35B (TSTA3))
    Alternative Name
    TSTA3/SDR4E1 (TSTA3 Products)
    Synonyms
    FX Protein, P35B Protein, SDR4E1 Protein, AI256181 Protein, Tstap35b Protein, p35b Protein, sdr4e1 Protein, TSTA3 Protein, zgc:101805 Protein, si:dkey-235d18none Protein, Fx Protein, tissue specific transplantation antigen P35B Protein, tissue specific transplantation antigen P35B L homeolog Protein, TSTA3 Protein, Tsta3 Protein, tsta3 Protein, tsta3.L Protein
    Background

    Background: GDP-L-Fucose Synthase is a NADP(H)-binding protein. It catalyzes the two-step epimerase and the reductase reactions in GDP-D-mannose metabolism, converting GDP-4-keto-6-D-dexoymannose to GDP-L-fucose. GDP-L-Fucose is the substrate of several fucosyltransferase, involving the expression of mamy glycoconjugates, including blood group ABH antigens and development adhesion antigens. Mutations in the TSTA3 gene may cause leukocyte adhesion deficiency type II.

    Synonym: GDP-L-Fucose Synthase, GDP-4-Keto-6-Deoxy-D-Mannose-3,5-Epimerase-4-Reductase, Protein FX, Red Cell NADP(H)-Binding Protein, Short-Chain Dehydrogenase/Reductase Family 4E Member 1, TSTA3, SDR4E1

    Molecular Weight
    37.0 kDa
    UniProt
    Q13630
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