NEU1 Protein (His tag)
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- Target See all NEU1 Proteins
- NEU1 (Sialidase 1 (Lysosomal Sialidase) (NEU1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This NEU1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Purification
- purified by chromatography
- Purity
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product NEU1 Protein
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Sialidase 1 (Lysosomal Sialidase) (NEU1) (AA 48-415) protein (His tag)
NEU1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Sialidase 1 (Lysosomal Sialidase) (NEU1) (AA 334-415) protein (GST tag)NEU1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Sialidase 1 (Lysosomal Sialidase) (NEU1) (AA 48-415) protein (His tag)Crystallography grade NEU1 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Sialidase 1 (Lysosomal Sialidase) (NEU1) (AA 42-409) protein (His tag)Crystallography grade NEU1 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Sialidase 1 (Lysosomal Sialidase) (NEU1) (AA 47-415) (Active) protein (His tag)NEU1 Origin: Human Host: Escherichia coli (E. coli) > 97 % AcA, CC Active
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- Comment
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Synonyms: Sialidase 1 (lysosomal sialidase), NANH, NEU, SIAL1
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 0.15 M NaCl, 10% glycerol,1 MM DTT
- Storage
- 4 °C
- Storage Comment
- Avoid repeated freezing and thawing cycles.
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- Target
- NEU1 (Sialidase 1 (Lysosomal Sialidase) (NEU1))
- Alternative Name
- NEU1 (NEU1 Products)
- Synonyms
- NANH Protein, NEU Protein, SIAL1 Protein, MGC81958 Protein, AA407268 Protein, AA407316 Protein, Aglp Protein, Apl Protein, Bat-7 Protein, Bat7 Protein, G9 Protein, Map-2 Protein, Neu Protein, Neu-1 Protein, neuraminidase 1 Protein, neuraminidase 1 (lysosomal sialidase) L homeolog Protein, NEU1 Protein, neu1.L Protein, neu1 Protein, Neu1 Protein
- Background
- NEU1 is a lysosomal enzyme that cleaves terminal sialic acid residues from substrates such as glycoproteins and glycolipids. In the lysosome, this enzyme is part of a heterotrimeric complex together with beta-galactosidase and cathepsin A. Mutations in this gene can lead to sialidosis, a lysosomal storage disease that can be type 1 (cherry red -myoclonus syndrome or normosomatic type), which is late-onset, or type 2 (the dysmorphic type), which occurs at an earlier age with increased severity. Recombinant human NEU1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 42.9 kDa (393aa), confirmed by MALDI-TOF
- NCBI Accession
- NP_000425
- Pathways
- SARS-CoV-2 Protein Interactome
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