NEU1 Protein (His tag)
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- Target See all NEU1 Proteins
- NEU1 (Sialidase 1 (Lysosomal Sialidase) (NEU1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Human Cells
- Purification tag / Conjugate
- This NEU1 protein is labelled with His tag.
- Purpose
- Recombinant Human Sialidase-1/NEU-1 Protein (His Tag)
- Sequence
- Glu48-Leu415
- Characteristics
- Recombinant Human N-acetyl-alpha-Neuraminidase 1 is produced by our Mammalian expression system and the target gene encoding Glu48-Leu415 is expressed with a 6His tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product NEU1 Protein
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Sialidase 1 (Lysosomal Sialidase) (NEU1) (AA 48-415) protein (His tag)
NEU1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Sialidase 1 (Lysosomal Sialidase) (NEU1) (AA 334-415) protein (GST tag)NEU1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Sialidase 1 (Lysosomal Sialidase) (NEU1) (AA 48-415) protein (His tag)Crystallography grade NEU1 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Sialidase 1 (Lysosomal Sialidase) (NEU1) (AA 42-409) protein (His tag)Crystallography grade NEU1 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Sialidase 1 (Lysosomal Sialidase) (NEU1) (AA 47-415) (Active) protein (His tag)NEU1 Origin: Human Host: Escherichia coli (E. coli) > 97 % AcA, CC Active
Sialidase 1 (Lysosomal Sialidase) (NEU1) (AA 141-286) (Active) protein (His tag)NEU1 Origin: Human Host: Escherichia coli (E. coli) > 90 % AcA, CC Active
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- Restrictions
- For Research Use only
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- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
- Storage
- -20 °C
- Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Target
- NEU1 (Sialidase 1 (Lysosomal Sialidase) (NEU1))
- Alternative Name
- Sialidase-1/NEU-1 (NEU1 Products)
- Synonyms
- NANH Protein, NEU Protein, SIAL1 Protein, MGC81958 Protein, AA407268 Protein, AA407316 Protein, Aglp Protein, Apl Protein, Bat-7 Protein, Bat7 Protein, G9 Protein, Map-2 Protein, Neu Protein, Neu-1 Protein, neuraminidase 1 Protein, neuraminidase 1 (lysosomal sialidase) L homeolog Protein, NEU1 Protein, neu1.L Protein, neu1 Protein, Neu1 Protein
- Background
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Background: Sialidase-1 belongs to the N-acetyl-a neuraminidase family. Sialidase-1 is expressed in many tissues, it is highly expressed in the pancreas, and weakly expressed in the brain. Sialidase-1 is a lysosomal enzyme, which cleaves terminal sialic acid residues from substrates such as glycoproteins and glycolipids. Deficiencies in the human enzyme Sialidase-1 leads to sialidosis, a rare lysosomal storage disease. Sialidase-1 has been shown to interact with Cathepsin A (protective protein), β-galactosidase and N-acetylgalactosamine-6-sulfate sulfatase in a multienzyme complex.
Synonym: Sialidase-1, Acetylneuraminyl Hydrolase, G9 Sialidase, Lysosomal Sialidase, N-Acetyl-Alpha-Neuraminidase 1, NEU1, NANH
- Molecular Weight
- 41.3 kDa
- UniProt
- Q99519
- Pathways
- SARS-CoV-2 Protein Interactome
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