ESM1 Protein (His tag)
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- Target See all ESM1 Proteins
- ESM1 (Endothelial Cell-Specific Molecule 1 (ESM1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This ESM1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product ESM1 Protein
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Endothelial Cell-Specific Molecule 1 (ESM1) protein (His tag)
ESM1 Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by SDS-PAGE
Endothelial Cell-Specific Molecule 1 (ESM1) (AA 1-184) protein (GST tag)ESM1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Endothelial Cell-Specific Molecule 1 (ESM1) (AA 85-184) protein (GST tag)ESM1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Endothelial Cell-Specific Molecule 1 (ESM1) protein (His tag)ESM1 Origin: Human Host: Human Cells Recombinant >90 % as determined by reducing SDS-PAGE.
Endothelial Cell-Specific Molecule 1 (ESM1) protein (His tag)ESM1 Origin: Mouse Host: Baculovirus infected Insect Cells Recombinant > 95 % as determined by SDS-PAGE
Endothelial Cell-Specific Molecule 1 (ESM1) (AA 20-184) protein (His tag)Crystallography grade ESM1 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Endothelial Cell-Specific Molecule 1 (ESM1) (AA 22-184) protein (His tag)Crystallography grade ESM1 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- Comment
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Synonyms: Endothelial cell-specific molecule 1, endocan
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM Tris-HCl buffer (pH 8.0) containing 2 M Urea, 10% glycerol
- Storage
- 4 °C
- Storage Comment
- Avoid repeated freezing and thawing cycles.
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- Target
- ESM1 (Endothelial Cell-Specific Molecule 1 (ESM1))
- Alternative Name
- ESM1 (ESM1 Products)
- Synonyms
- ESM1 Protein, zgc:153027 Protein, 0610042H23Rik Protein, AV004503 Protein, ESM-1 Protein, Pg25 Protein, endocan Protein, endothelial cell specific molecule 1 Protein, endothelial cell-specific molecule 1 Protein, ESM1 Protein, esm1 Protein, Esm1 Protein
- Background
- Endothelial cell-specific molecule 1, also known as ESM1, is a proteoglycan secreted by endothelial cells and its mRNA expression is regulated by inflammatory cytokines. ESM1 expression has also been detected in different epithelia and in adipocytes. The expression of endocan is upregulated by TNF alpha, IL1 beta, or lipopolysaccharide and downregulated by IFN gamma. Genetically engineered cells overexpressing endocan has been shown to induce tumor formation, suggesting that ESM1 may be involved in the pathophysiology of tumor growth in vivo. Recombinant human ESM1 protein, fused to His-tag at N-terminus, was expressed in E.coli
- Molecular Weight
- 20.5 kDa (188aa)
- NCBI Accession
- NP_008967
- Pathways
- Growth Factor Binding
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