ESM1 Protein (His tag)
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- Target See all ESM1 Proteins
- ESM1 (Endothelial Cell-Specific Molecule 1 (ESM1))
- Protein Type
- Recombinant
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Origin
- Mouse
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Source
- Baculovirus infected Insect Cells
- Purification tag / Conjugate
- This ESM1 protein is labelled with His tag.
- Purpose
- Recombinant Mouse ESM1/Endocan Protein (Baculovirus, His Tag)
- Sequence
- Met1-Arg184
- Characteristics
- A DNA sequence encoding the mouse TLR2 (Q9QYY7) (Met1-Arg184) was fused with a polyhistidine tag at the C-terminus.
- Purity
- > 95 % as determined by SDS-PAGE
- Endotoxin Level
- < 1.0 EU per μg of the protein as determined by the LAL method.
- Top Product
- Discover our top product ESM1 Protein
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Endothelial Cell-Specific Molecule 1 (ESM1) protein (His tag)
ESM1 Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by SDS-PAGE
Endothelial Cell-Specific Molecule 1 (ESM1) (AA 1-184) protein (GST tag)ESM1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Endothelial Cell-Specific Molecule 1 (ESM1) (AA 85-184) protein (GST tag)ESM1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Endothelial Cell-Specific Molecule 1 (ESM1) protein (His tag)ESM1 Origin: Human Host: Human Cells Recombinant >90 % as determined by reducing SDS-PAGE.
Endothelial Cell-Specific Molecule 1 (ESM1) (AA 20-184) protein (His tag)Crystallography grade ESM1 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Endothelial Cell-Specific Molecule 1 (ESM1) (AA 22-184) protein (His tag)Crystallography grade ESM1 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile 20 mM Tris, 500 mM NaCl, pH 8.0, 10 % glycerol
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- ESM1 (Endothelial Cell-Specific Molecule 1 (ESM1))
- Alternative Name
- ESM1/Endocan (ESM1 Products)
- Synonyms
- ESM1 Protein, zgc:153027 Protein, 0610042H23Rik Protein, AV004503 Protein, ESM-1 Protein, Pg25 Protein, endocan Protein, endothelial cell specific molecule 1 Protein, endothelial cell-specific molecule 1 Protein, ESM1 Protein, esm1 Protein, Esm1 Protein
- Background
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Background: ESM1 is a secreted protein which is produced by adipocytes. It has been noticed that ESM1 may play some role in obesity-associated vascular disease since circulating ESM-1 levels are reduced in the overweight and obese. ESM1 is mainly expressed in the endothelial cells in human lung and kidney tissues. The expression of ESM1 gene is regulated by cytokines, suggesting that it may play a role in endothelium-dependent pathological disorders. Recently, ESM1 has been described as a specific biomarker of tip cells during neoangiogenesis. Its expression has been shown to be increase in presence of pro-angiogenic growth factors such as VEGF or FGF-2. In hypervascularized cancers, overexpression of endocan has been detected by immunohistochemistry using monoclonal antibodies against ESM1.
Synonym: Endothelial cell-specific molecule 1, ESM-1, Esm1, Endocan
- Molecular Weight
- 19.1 kDa
- UniProt
- Q9QYY7
- Pathways
- Growth Factor Binding
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