XRCC3 Protein (His tag)

Catalog No. ABIN1098726

Product Details

Target: XRCC3 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 3 (XRCC3))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This XRCC3 protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Purity: > 85 % by SDS - PAGE

Application Details

Comment:

Synonyms: X-ray repair cross complementing protein 3, RAD51-like

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/ml (determined by Bradford assay)

Buffer: 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.4 M Urea

Storage: 4 °C

Storage Comment: Avoid repeated freezing and thawing cycles.

Target Details

Target: XRCC3 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 3 (XRCC3))

Alternative Name: XRCC3 (XRCC3 Products)

Synonyms: CMM6 Protein, 4432412E01Rik Protein, AI182522 Protein, AW537713 Protein, MGC69118 Protein, im:7142103 Protein, zgc:101608 Protein, si:dkey-11b8.1 Protein, xrcc3 Protein, XRCC3 Protein, X-ray repair cross complementing 3 Protein, X-ray repair complementing defective repair in Chinese hamster cells 3 Protein, X-ray repair complementing defective repair in Chinese hamster cells 3 L homeolog Protein, XRCC3 Protein, Xrcc3 Protein, xrcc3.L Protein, xrcc3 Protein

Background: XRCC3, also known as RAD51-like, belongs to the RecA family and RAD51 subfamily. It participates in homologous recombination to maintain chromosome stability and repair DNA damage. This protein functionally complements Chinese hamster irs1SF, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents and is chromosomally unstable. Recombinant human XRCC3 protein, fused to His-tag at N-terminus, was expressed in E.coli.

Molecular Weight: 40.0 kDa (366aa)

NCBI Accession: NP_005423

Pathways: DNA Damage Repair