REG4 Protein (AA 23-158) (His tag)

Catalog No. ABIN1691598

Product Details

Target: REG4 (Regenerating Islet-Derived Family, Member 4 (REG4))

Protein Type: Recombinant

Protein Characteristics: AA 23-158

Origin: Human

Source: Human Cells

Purification tag / Conjugate: This REG4 protein is labelled with His tag.

Purpose: Recombinant Human Regenerating Islet-Derived Protein 4/RELP (C-6His)

Sequence: DIIMRPSCAP GWFYHKSNCY GYFRKLRNWS DAELECQSYG NGAHLASILS LKEASTIAEY ISGYQRSQPI WIGLHDPQKR QQWQWIDGAM YLYRSWSGKS MGGNKHCAEM SSNNNFLTWS SNECNKRQHF LCKYRPVDHH HHHH

Characteristics: Recombinant Human Regenerating islet-derived protein 4/REG4 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Asp23­Pro158) of Human REG4 fused with a polyhistidine tag at the C-terminus.

Purity: > 95 % as determined by reducing SDS-PAGE.

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.2.

Handling Advice: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Storage: 4 °C/-20 °C/-80 °C

Storage Comment: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 5 months

Target Details

Target: REG4 (Regenerating Islet-Derived Family, Member 4 (REG4))

Alternative Name: REG4 (REG4 Products)

Synonyms: GISP Protein, REG-IV Protein, RELP Protein, 2010002L15Rik Protein, regenerating family member 4 Protein, regenerating islet-derived family, member 4 Protein, Reg4 Protein, REG4 Protein

Sub Type: Fusionprotein

Background: REG4 is a secreted contains one C-type lectin domain, high expressed in the gastrointestinal tract, including jejunum, ileum, appendix, pancreas and small intestine. REG4 can be up-regulated by mucosal injury from active Crohn’s disease or ulcerative colitis. In the acid environment, REG4 can maintain carbohydrate recognition activity. REG4 may be involved in inflammatory and metaplastic response of the gastrointestinal epithelium.
Alternative Names: Regenerating islet-derived protein 4, Gastrointestinal secretory protein, REG-like protein, Regenerating islet-derived protein IV, GISP, RELP, REG4

Molecular Weight: 19.2 kDa

UniProt: Q9BYZ8