REG4 Protein (Fc Tag)
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- Target See all REG4 Proteins
- REG4 (Regenerating Islet-Derived Family, Member 4 (REG4))
- Protein Type
- Recombinant
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Origin
- Rat
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This REG4 protein is labelled with Fc Tag.
- Purpose
- Recombinant Rat REG4 Protein (Fc Tag)
- Sequence
- Met1-Pro157
- Characteristics
- A DNA sequence encoding the rat REG4 (Q68AX7) (Met1-Pro157) was expressed, fused with the Fc region of human IgG1 at the C-terminus.
- Purity
- > 80 % as determined by SDS-PAGE
- Endotoxin Level
- < 1.0 EU per μg of the protein as determined by the LAL method
- Top Product
- Discover our top product REG4 Protein
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Regenerating Islet-Derived Family, Member 4 (REG4) protein (His tag)
REG4 Origin: Rat Host: Escherichia coli (E. coli) Recombinant >85 % as determined by reducing SDS-PAGE.
Regenerating Islet-Derived Family, Member 4 (REG4) protein (His tag)REG4 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant >85 % as determined by reducing SDS-PAGE.
Regenerating Islet-Derived Family, Member 4 (REG4) (AA 1-158) protein (GST tag)REG4 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Regenerating Islet-Derived Family, Member 4 (REG4) (Active) protein (His tag)REG4 Origin: Mouse Host: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE Active
Regenerating Islet-Derived Family, Member 4 (REG4) protein (His tag)REG4 Origin: Rat Host: HEK-293 Cells Recombinant > 78 % as determined by SDS-PAGE
Regenerating Islet-Derived Family, Member 4 (REG4) (AA 23-158) protein (His tag)Crystallography grade REG4 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Regenerating Islet-Derived Family, Member 4 (REG4) (AA 23-157) protein (His tag)Crystallography grade REG4 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile PBS, pH 7.4
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- REG4 (Regenerating Islet-Derived Family, Member 4 (REG4))
- Alternative Name
- REG4 (REG4 Products)
- Synonyms
- GISP Protein, REG-IV Protein, RELP Protein, 2010002L15Rik Protein, regenerating family member 4 Protein, regenerating islet-derived family, member 4 Protein, Reg4 Protein, REG4 Protein
- Background
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Background: Regenerating islet-derived protein 4, also known as REG-like protein, REG4, GISP and RELP, a member of the regenerating gene family belonging to the calcium (C-type) dependent lectin superfamily, has been found to be involved in malignancy in several different organs including the stomach, colorectum, pancreas and prostate. It is highly expressed in the gastrointestinal tract and markedly up-regulated in colon adenocarcinoma, pancreatic cancer, gastric adenocarcinoma, and inflammatory bowel disease. Expression of the Reg4 in different cell types has been associated with regeneration, cell growth and cell survival, cell adhesion and resistance to apoptosis. REG4 protein overexpression is associated with an unfavorable response to preoperative chemoradiotherapy and may be used as a predictive biomarker clinically. REG4 may play an important role in the development and progression of colorectal cancer, as well as in intestinal morphogenesis and epithelium restitution.
Synonym: REG4
- Molecular Weight
- 42.9 kDa
- UniProt
- Q68AX7
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