Ephrin B1 Protein (EFNB1) (AA 28-232) (His tag)
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- Target See all Ephrin B1 (EFNB1) Proteins
- Ephrin B1 (EFNB1)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 28-232
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Ephrin B1 protein is labelled with His tag.
- Sequence
- AA 28-232
- Characteristics
- This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 23.2 kDa. The protein migrates as 32-40 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Purity
- >95 % as determined by SDS-PAGE.
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product EFNB1 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Handling Advice
- Please avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
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- Target
- Ephrin B1 (EFNB1)
- Alternative Name
- Ephrin-B1 (EFNB1 Products)
- Synonyms
- EFNB1 Protein, LERK2 Protein, Cek5-L Protein, EFL-3 Protein, Elk-L Protein, Epl2 Protein, Eplg2 Protein, LERK-2 Protein, Lerk2 Protein, Stra1 Protein, CFND Protein, CFNS Protein, EFL3 Protein, EPLG2 Protein, cfnd Protein, cfns Protein, efl3 Protein, efnb1-A Protein, ephrinB1 Protein, eplg2 Protein, lerk2 Protein, ephrin B1 Protein, ephrin-B1 Protein, ephrin-B1 L homeolog Protein, EFNB1 Protein, Efnb1 Protein, efnb1 Protein, efnb1.L Protein
- Background
- Ephrin-B1 (EFNB1) is also known as EFL-3, ELK ligand, EPH-related receptor tyrosine kinase ligand 2 (LERK-2), which belongs to the ephrin family. EFNB1 contains one ephrin RBD (ephrin receptor-binding) domain. EFNB1 binds to the receptor tyrosine kinases EPHB1 and EPHA1. EFNB1 binds to, and induce the collapse of, commissural axons/growth cones in vitro. EFNB1 may play a role in constraining the orientation of longitudinally projecting axons. EFNB1 interacts with GRIP1 and GRIP2.
- Molecular Weight
- 23.6 kDa
- NCBI Accession
- NP_004420
- Pathways
- RTK Signaling
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