EFNA4 Protein (AA 26-171) (His tag)
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- Target See all EFNA4 Proteins
- EFNA4 (Ephrin A4 (EFNA4))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 26-171
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This EFNA4 protein is labelled with His tag.
- Sequence
- AA 26-171
- Characteristics
- This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 17.2 kDa. The protein migrates as 20-22 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Purity
- >95 % as determined by SDS-PAGE.
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product EFNA4 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Handling Advice
- Please avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
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- Target
- EFNA4 (Ephrin A4 (EFNA4))
- Alternative Name
- Ephrin-A4 (EFNA4 Products)
- Synonyms
- EFNA4 Protein, EFL-4 Protein, Epl4 Protein, LERK-4 Protein, EFL4 Protein, EPLG4 Protein, LERK4 Protein, ephrin A4 Protein, ephrin-A4 L homeolog Protein, ephrin-A4 Protein, EFNA4 Protein, efna4.L Protein, efna4 Protein, Efna4 Protein
- Background
- Ephrin-A4 (EFNA4) is also known as EPH-related receptor tyrosine kinase ligand 4 (LERK4), EPLG4, which belongs to the ephrin family. EFNA4 contains one ephrin RBD (ephrin receptor-binding) domain. EFNA4 is cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. EFNA4 binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. EFNA4 may play a role in the interaction between activated B-lymphocytes and dendritic cells in tonsils.
- Molecular Weight
- 17.5 kDa
- Pathways
- RTK Signaling
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