IL21 Receptor Protein (AA 20-236) (His tag)
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- Target See all IL21 Receptor (IL21R) Proteins
- IL21 Receptor (IL21R) (Interleukin 21 Receptor (IL21R))
- Protein Type
- Recombinant
- Biological Activity
- Active
- Protein Characteristics
- AA 20-236
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This IL21 Receptor protein is labelled with His tag.
- Sequence
- AA 20-236
- Characteristics
- This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 25.8 kDa. The protein migrates as 42-50 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Purity
- >92 % as determined by SDS-PAGE.
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product IL21R Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Handling Advice
- Please avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
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- Target
- IL21 Receptor (IL21R) (Interleukin 21 Receptor (IL21R))
- Alternative Name
- IL-21 R (IL21R Products)
- Synonyms
- IL21R Protein, il-21ra.a Protein, CD360 Protein, NILR Protein, interleukin 21 receptor Protein, interleukin 21 receptor, tandem duplicate 1 Protein, IL21R Protein, il21r.1 Protein, Il21r Protein
- Background
- Interleukin-21 receptor (IL21R) is also known as CD antigen CD360, Novel interleukin receptor (NILR), is a receptor for interleukin-21 and belongs to the type I cytokine receptor family or type 4 subfamily. IL21R contains two fibronectin type-III domains. IL21R is selectively expressed in lymphoid tissues and most highly expressed in thymus and spleen. IL21R transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells.
- Molecular Weight
- 26.1 kDa
- Pathways
- JAK-STAT Signaling
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