PIGR Protein (AA 19-638) (His tag)
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- Target See all PIGR Proteins
- PIGR (Polymeric Immunoglobulin Receptor (PIGR))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 19-638
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This PIGR protein is labelled with His tag.
- Sequence
- AA 19-638
- Characteristics
- This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 68.7 kDa. The protein migrates as 85-95 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Purity
- >95 % as determined by SDS-PAGE.
- Sterility
- 0.22 μm filtered
- Endotoxin Level
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product PIGR Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Handling Advice
- Please avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C-8 °C), After reconstitution under sterile conditions for 1 month (4 °C-8 °C) or 3 months (-20 °C to -70 °C).
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- Target
- PIGR (Polymeric Immunoglobulin Receptor (PIGR))
- Alternative Name
- pIgR (PIGR Products)
- Synonyms
- DKFZp469G1013 Protein, RNPIGR2 Protein, pIgA-R Protein, polymeric immunoglobulin receptor Protein, PIGR Protein, Pigr Protein
- Background
- Polymeric immunoglobulin receptor (PIGR) is also known as Poly-Ig receptor, which can be cleaved into membrane secretory component (SC). PIGR is a type I transmembrane glycoprotein or a member of the immunoglobulin superfamily, and is synthesized by secretory epithelial cells and delivered to the basolateral plasma membrane where it can bind larger polymers of IgA (pIgA ) and pentameric IgM. The complex is then transported across the cell to be secreted at the apical surface. During this process a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment.
- Molecular Weight
- 68.7 kDa
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