PIGR Protein (AA 19-638) (Fc Tag)

Catalog No. ABIN1945399

Product Details

Target: PIGR (Polymeric Immunoglobulin Receptor (PIGR))

Protein Type: Recombinant

Protein Characteristics: AA 19-638

Origin: Human

Source: Human Cells

Purification tag / Conjugate: This PIGR protein is labelled with Fc Tag.

Purpose: Recombinant Human Polymeric Immunoglobulin Receptor/PIgR (C-Fc)

Sequence: KSPIFGPEEV NSVEGNSVSI TCYYPPTSVN RHTRKYWCRQ GARGGCITLI SSEGYVSSKY AGRANLTNFP ENGTFVVNIA QLSQDDSGRY KCGLGINSRG LSFDVSLEVS QGPGLLNDTK VYTVDLGRTV TINCPFKTEN AQKRKSLYKQ IGLYPVLVID SSGYVNPNYT GRIRLDIQGT GQLLFSVVIN QLRLSDAGQY LCQAGDDSNS NKKNADLQVL KPEPELVYED LRGSVTFHCA LGPEVANVAK FLCRQSSGEN CDVVVNTLGK RAPAFEGRIL LNPQDKDGSF SVVITGLRKE DAGRYLCGAH SDGQLQEGSP IQAWQLFVNE ESTIPRSPTV VKGVAGGSVA VLCPYNRKES KSIKYWCLWE GAQNGRCPLL VDSEGWVKAQ YEGRLSLLEE PGNGTFTVIL NQLTSRDAGF YWCLTNGDTL WRTTVEIKII EGEPNLKVPG NVTAVLGETL KVPCHFPCKF SSYEKYWCKW NNTGCQALPS QDEGPSKAFV NCDENSRLVS LTLNLVTRAD EGWYWCGVKQ GHFYGETAAV YVAVEERKAA GSRDVSLAKA DAAPDEKVLD SGFREIENKA IQDPRLFAEE KAVADTRDQA DGSRASVDSG SSEEQGGSSR VDDIEGRMDE PKSCDKTHTC PPCPAPELLG GPSVFLFPPK PKDTLMISRT PEVTCVVVDV SHEDPEVKFN WYVDGVEVHN AKTKPREEQY NSTYRVVSVL TVLHQDWLNG KEYKCKVSNK ALPAPIEKTI SKAKGQPREP QVYTLPPSRE EMTKNQVSLT CLVKGFYPSD IAVEWESNGQ PENNYKTTPP VLDSDGSFFL YSKLTVDKSR WQQGNVFSCS VMHEALHNHY TQKSLSLSPG K

Characteristics: Recombinant Human PIGR is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Lys19­Arg638 ) of Human PIGR fused with a FC tag at the C-terminus.

Purity: > 95 % as determined by reducing SDS-PAGE.

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM Tris,150 mM NaCl, pH 8.0.

Handling Advice: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Storage: 4 °C/-20 °C/-80 °C

Storage Comment: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Target Details

Target: PIGR (Polymeric Immunoglobulin Receptor (PIGR))

Alternative Name: Polymeric Immunoglobulin Receptor/PIgR (PIGR Products)

Synonyms: DKFZp469G1013 Protein, RNPIGR2 Protein, pIgA-R Protein, polymeric immunoglobulin receptor Protein, PIGR Protein, Pigr Protein

Background: PIGR binds polymeric IgA and IgM at the basolateral surface of epithelial cells. The complex is then transported across the cell to be secreted at the apical surface. During this process a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment.

Molecular Weight: 95 kDa

UniProt: P01833