Decorin Protein (DCN) (His tag)
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- Target See all Decorin (DCN) Proteins
- Decorin (DCN)
- Protein Type
- Recombinant
- Biological Activity
- Active
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Decorin protein is labelled with His tag.
- Application
- Western Blotting (WB)
- Characteristics
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Measured by its ability to modulate collagen fibrillogenesis. At 5 μg/mL, rhDecorin can significantly delay the rate of type I collagen fibrillogenesis.
- Purity
- >95 % as determined by SDS-PAGE.
- Top Product
- Discover our top product DCN Protein
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Decorin (DCN) (AA 1-359) protein (GST tag)
DCN Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Decorin (DCN) protein (His tag)DCN Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by SDS-PAGE
Decorin (DCN) (AA 36-195) protein (His-IF2DI Tag)DCN Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Decorin (DCN) (AA 35-354) protein (His tag)DCN Origin: Mouse Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
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- Application Notes
- This recombinant protein can be used for WB. For research use only.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Storage
- -80 °C,-20 °C
- Storage Comment
- Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
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- Target
- Decorin (DCN)
- Alternative Name
- Bone Proteoglycan II (DCN Products)
- Synonyms
- CSCD Protein, DSPG2 Protein, PG40 Protein, PGII Protein, PGS2 Protein, SLRR1B Protein, DC Protein, mDcn Protein, cscd Protein, dspg2 Protein, pg40 Protein, pgii Protein, pgs2 Protein, slrr1b Protein, decorin Protein, decorin L homeolog Protein, DCN Protein, Dcn Protein, dcn.L Protein, dcn Protein
- Background
- Decorin is also known as bone proteoglycan II, PGS2, SLRR1B, DCN, DSPG2 and PG40, is a secreted chondroitin /dermatan sulfate proteoglycan in the family of small leucine-rich proteoglycans (SLRPs). Decorin is a small cellular or pericellular matrix proteoglycan and is closely related in structure to biglycan protein. Decorin and biglycan are thought to be the result of a gene duplication. This protein is a component of connective tissue, binds to type I collagen fibrils, and plays a role in matrix assembly. Decorin appears to influence fibrillogenesis, and also interacts with fibronectin, thrombospondin, the complement component C1q, epidermal growth factor receptor (EGFR) and transforming growth factor-beta (TGF-beta). Defects in DCN are the cause of congenital stromal corneal dystrophy (CSCD).
- Molecular Weight
- 38.8 kDa
- Gene ID
- 1634
- NCBI Accession
- NP_001911
- UniProt
- P07585
- Pathways
- Glycosaminoglycan Metabolic Process
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