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CD79b Protein (Fc Tag)

CD79B Origin: Human Host: HEK-293 Cells Recombinant >92 % as determined by SDS-PAGE. WB
Catalog No. ABIN2566441
  • Target See all CD79b (CD79B) Proteins
    CD79b (CD79B) (CD79b Molecule, Immunoglobulin-Associated beta (CD79B))
    Protein Type
    Recombinant
    Origin
    • 17
    • 5
    • 2
    • 2
    • 2
    Human
    Source
    • 14
    • 6
    • 4
    • 2
    • 2
    HEK-293 Cells
    Purification tag / Conjugate
    This CD79b protein is labelled with Fc Tag.
    Application
    Western Blotting (WB)
    Characteristics

    Fusion tag: C-Fc Tag

    Purity
    >92 % as determined by SDS-PAGE.
    Top Product
    Discover our top product CD79B Protein
  • Application Notes
    This recombinant protein can be used for WB. For research use only.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    50 mM tris, 100 mM glycine, pH 7.5
    Storage
    -80 °C,-20 °C
    Storage Comment
    Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
  • Target
    CD79b (CD79B) (CD79b Molecule, Immunoglobulin-Associated beta (CD79B))
    Alternative Name
    CD79 B (CD79B Products)
    Synonyms
    B29 Protein, Ig-beta Protein, Igb Protein, Igbeta Protein, AGM6 Protein, IGB Protein, CD79B antigen Protein, CD79b molecule Protein, Cd79b Protein, CD79B Protein
    Background
    B-cell antigen receptor complex-associated protein beta chain (CD79b) is also known as B-cell-specific glycoprotein B29, Ig-beta,Immunoglobulin-associated B29 protein, B29 and IGB, which is a single-pass type I membrane protein containing one Ig-like V-type ( immunoglobulin-like ) domain and one ITAM domain.CD79b is required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR).CD79b can enhance phosphorylation of CD79A, possibly by recruiting kinases which phosphorylate CD79A or by recruiting proteins which bind to CD79A and protect it from dephosphorylation. Defects in CD79b are the cause of agammaglobulinemia type 6 (AGM6) that is a primary immunodeficiency characterized by profoundly low or absent serum antibodies and low or absent circulating B cells due to an early block of B-cell development.
    Molecular Weight
    41.8 kDa
    Gene ID
    974
    NCBI Accession
    NP_000617
    UniProt
    P40259
    Pathways
    BCR Signaling
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