Bestrophin 3 Protein (BEST3) (Transcript Variant 2) (Myc-DYKDDDDK Tag)
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- Target See all Bestrophin 3 (BEST3) Proteins
- Bestrophin 3 (BEST3)
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 2
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Bestrophin 3 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human Bestrophin-3 (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product BEST3 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- Bestrophin 3 (BEST3)
- Alternative Name
- Bestrophin-3 (BEST3 Products)
- Synonyms
- CG12327 Protein, Dmel\\CG12327 Protein, dbest3 Protein, best-3 Protein, BEST3 Protein, VMD2L3 Protein, Vmd2l3 Protein, mBest4 Protein, bestrophin-3 Protein, bestrophin 3 Protein, Bestrophin 3 Protein, BEST3 Protein, Best3 Protein, best3 Protein
- Background
- BEST3 belongs to the bestrophin family of anion channels, which includes BEST1 (MIM 607854), the gene mutant in vitelliform macular dystrophy (VMD MIM 153700), and 2 other BEST1-like genes, BEST2 (MIM 607335) and BEST4 (MIM 607336). Bestrophins are transmembrane (TM) proteins that share a homology region containing a high content of aromatic residues, including an invariant arg-phe-pro (RFP) motif. The bestrophin genes share a conserved gene structure, with almost identical sizes of the 8 RFP-TM domain-encoding exons and highly conserved exon-intron boundaries. Each of the 4 bestrophin genes has a unique 3-prime end of variable length (Stohr et al., 2002 [PubMed 12032738] Tsunenari et al., 2003 [PubMed 12907679]).[supplied by OMIM, Mar 2008].
- Molecular Weight
- 50.8 kDa
- NCBI Accession
- NP_689652
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