KCNQ4 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)
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- Target See all KCNQ4 Proteins
- KCNQ4 (Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 4 (KCNQ4))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 2
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This KCNQ4 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human KCNQ4 (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product KCNQ4 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- KCNQ4 (Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 4 (KCNQ4))
- Alternative Name
- Kcnq4 (KCNQ4 Products)
- Synonyms
- KCNQ4 Protein, k(v)7.4 Protein, kv7.4 Protein, DFNA2 Protein, DFNA2A Protein, KV7.4 Protein, potassium voltage-gated channel subfamily Q member 4 Protein, potassium channel, voltage gated KQT-like subfamily Q, member 4 Protein, potassium voltage-gated channel, subfamily Q, member 4 Protein, KCNQ4 Protein, kcnq4 Protein, Kcnq4 Protein
- Background
- Probably important in the regulation of neuronal excitability. May underlie a potassium current involved in regulating the excitability of sensory cells of the cochlea. KCNQ4 channels are blocked by linopirdin, XE991 and bepridil, whereas clofilium is without significant effect. Muscarinic agonist oxotremorine-M strongly suppress KCNQ4 current in CHO cells in which cloned KCNQ4 channels were coexpressed with M1 muscarinic receptors. [UniProtKB/Swiss-Prot Function]
- Molecular Weight
- 71 kDa
- NCBI Accession
- NP_751895
- Pathways
- Sensory Perception of Sound
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