LY96 Protein (Myc-DYKDDDDK Tag)
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- Target See all LY96 Proteins
- LY96 (Lymphocyte Antigen 96 (LY96))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This LY96 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human MD-2 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product LY96 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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Amniotic Fluid Soluble Myeloid Differentiation-2 (sMD-2) as Regulator of Intra-amniotic Inflammation in Infection-induced Preterm Birth." in: American journal of reproductive immunology (New York, N.Y. : 1989), Vol. 73, Issue 6, pp. 507-21, (2015) (PubMed).
: "
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Amniotic Fluid Soluble Myeloid Differentiation-2 (sMD-2) as Regulator of Intra-amniotic Inflammation in Infection-induced Preterm Birth." in: American journal of reproductive immunology (New York, N.Y. : 1989), Vol. 73, Issue 6, pp. 507-21, (2015) (PubMed).
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- Target
- LY96 (Lymphocyte Antigen 96 (LY96))
- Alternative Name
- Md-2 (LY96 Products)
- Synonyms
- MD2 Protein, ESOP-1 Protein, MD-2 Protein, ly-96 Protein, Ly-96 Protein, Md2 Protein, lymphocyte antigen 96 Protein, LY96 Protein, Ly96 Protein
- Background
- This gene encodes a protein which associates with toll-like receptor 4 on the cell surface and confers responsiveness to lipopolysaccyaride (LPS), thus providing a link between the receptor and LPS signaling. Studies of the mouse ortholog suggest that this gene may be involved in endotoxin neutralization. Alternative splicing results in multiple transcript variants encoding different isoforms.
- Molecular Weight
- 18.4 kDa
- NCBI Accession
- NP_056179
- Pathways
- TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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