MMP14 Protein (AA 112-582) (His-SUMO Tag)
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- Target See all MMP14 Proteins
- MMP14 (Matrix Metallopeptidase 14 (Membrane-inserted) (MMP14))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 112-582
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This MMP14 protein is labelled with His-SUMO Tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- YAIQGLKWQH NEITFCIQNY TPKVGEYATY EAIRKAFRVW ESATPLRFRE VPYAYIREGH EKQADIMIFF AEGFHGDSTP FDGEGGFLAH AYFPGPNIGG DTHFDSAEPW TVRNEDLNGN DIFLVAVHEL GHALGLEHSS DPSAIMAPFY QWMDTENFVL PDDDRRGIQQ LYGGESGFPT KMPPQPRTTS RPSVPDKPKN PTYGPNICDG NFDTVAMLRG EMFVFKERWF WRVRNNQVMD GYPMPIGQFW RGLPASINTA YERKDGKFVF FKGDKHWVFD EASLEPGYPK HIKELGRGLP TDKIDAALFW MPNGKTYFFR GNKYYRFNEE LRAVDSEYPK NIKVWEGIPE SPRGSFMGSD EVFTYFYKGN KYWKFNNQKL KVEPGYPKSA LRDWMGCPSG GRPDEGTEEE TEVIIIEVDE EGGGAVSAAA VVLPVLLLLL VLAVGLAVFF FRRHGTPRRL LYCQRSLLDK V
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product MMP14 Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- MMP14 (Matrix Metallopeptidase 14 (Membrane-inserted) (MMP14))
- Alternative Name
- MMP14 (MMP14 Products)
- Synonyms
- MMP1 Protein, MMP-14 Protein, MMP-X1 Protein, MT-MMP Protein, MT-MMP 1 Protein, MT1-MMP Protein, MT1MMP Protein, MTMMP1 Protein, mmp-x1 Protein, mt1-mmp Protein, mtmmp1 Protein, AI325305 Protein, MT-MMP-1 Protein, sabe Protein, Mt1-mmp Protein, MT-MMPbeta Protein, cb386 Protein, sb:cb386 Protein, wu:fb72b09 Protein, mmp14 Protein, matrix metallopeptidase 14 Protein, matrix metallopeptidase 14 (membrane-inserted) Protein, matrix metallopeptidase 14b (membrane-inserted) Protein, matrix metallopeptidase 14a (membrane-inserted) Protein, matrix metallopeptidase 14 L homeolog Protein, MMP14 Protein, mmp14 Protein, Mmp14 Protein, mmp14b Protein, mmp14a Protein, mmp14.L Protein
- Background
- Ses to specifically activate progelatinase A. May thus trigger invasion by tumor cells by activating progelatinase A on the tumor cell surface. May be involved in actin cytoskeleton reorganization by cleaving PTK7. Acts as a positive regulator of cell growth and migration via activation of MMP15. Involved in the formation of the fibrovascular tissues in association with pro-MMP2.
- Molecular Weight
- 69.8 kDa
- UniProt
- P50281
- Pathways
- Autophagy
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