USH1C Protein (AA 1-533) (His tag)
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- Target See all USH1C Proteins
- USH1C (Usher Syndrome 1C (Autosomal Recessive, Severe) (USH1C))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-533
- Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This USH1C protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- Harmonin, 1-533aa, Human, His-tagged, Recombinant, E.coli
- Purity
- > 95 % by SDS - PAGE
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20 mM Tris-HCl buffer (pH 8.0) containing 20% glycerol.
- Storage
- 4 °C
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- Target
- USH1C (Usher Syndrome 1C (Autosomal Recessive, Severe) (USH1C))
- Alternative Name
- Harmonin (USH1C Products)
- Synonyms
- AIE-75 Protein, DFNB18 Protein, DFNB18A Protein, NY-CO-37 Protein, NY-CO-38 Protein, PDZ-45 Protein, PDZ-73 Protein, PDZ-73/NY-CO-38 Protein, PDZ73 Protein, PDZD7C Protein, ush1cpst Protein, 2010016F01Rik Protein, harmonin Protein, zgc:136806 Protein, ush1c Protein, USH1 protein network component harmonin Protein, harmonin Protein, Usher syndrome 1C Protein, USH1 protein network component harmonin L homeolog Protein, USH1C Protein, CpipJ_CPIJ012732 Protein, Ush1c Protein, ush1c Protein, ush1c.L Protein
- Background
- Harmonin, product encoded by USH1c gene, is a scaffold protein that functions in the assembly of Usher protein complexes. Usher syndrome type I caused by mutations in USH1C is an autosomal recessive sensory defect involving congenital profound sensorineural deafness, vestibular dysfunction, and blindness due to progressive retinitis pigmentosa. Hormonin has the ability to bind to many other proteins in cell membranes and coordinates their activities. Recombinant human Harmonin protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: Harmonin, USH1C, AIE-75, DFNB18, NY-CO-37, NY-CO-38, PDZ-45, PDZ-73, PDZ-73/NY-CO-38, AIE 75, AIE75, Antigen NY CO 38/NY CO 37, Autoimmune enteropathy related antigen AIE 75, Autoimmune enteropathy related antigen AIE75, Deafness autosomal recessive 18, DFNB 18, NY CO 37, NY CO 38, PDZ 45, PDZ 73, PDZ 73 protein, PDZ 73/NY CO 38, PDZ45, PDZ73, PDZ73 protein, Renal carcinoma antigen NY REN 3, USH 1C, Ush1cpst, Usher syndrome 1C, Usher syndrome type 1C protein, Usher syndrome 1C (autosomal recessive severe). NCBI no.: AAH16057
- Molecular Weight
- 64.6 kDa (570aa)
- Pathways
- Sensory Perception of Sound
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