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USH1C Protein (AA 1-533) (His-SUMO Tag)

USH1C Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
Catalog No. ABIN5712005
  • Target See all USH1C Proteins
    USH1C (Usher Syndrome 1C (Autosomal Recessive, Severe) (USH1C))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-533
    Origin
    Human
    Source
    • 2
    • 2
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This USH1C protein is labelled with His-SUMO Tag.
    Application
    SDS-PAGE (SDS)
    Sequence
    MDRKVAREFR HKVDFLIEND AEKDYLYDVL RMYHQTMDVA VLVGDLKLVI NEPSRLPLFD AIRPLIPLKH QVEYDQLTPR RSRKLKEVRL DRLHPEGLGL SVRGGLEFGC GLFISHLIKG GQADSVGLQV GDEIVRINGY SISSCTHEEV INLIRTKKTV SIKVRHIGLI PVKSSPDEPL TWQYVDQFVS ESGGVRGSLG SPGNRENKEK KVFISLVGSR GLGCSISSGP IQKPGIFISH VKPGSLSAEV GLEIGDQIVE VNGVDFSNLD HKEGRELFMT DRERLAEARQ RELQRQELLM QKRLAMESNK ILQEQQEMER QRRKEIAQKA AEENERYRKE MEQIVEEEEK FKKQWEEDWG SKEQLLLPKT ITAEVHPVPL RKPKYDQGVE PELEPADDLD GGTEEQGEQD FRKYEEGFDP YSMFTPEQIM GKDVRLLRIK KEGSLDLALE GGVDSPIGKV VVSAVYERGA AERHGGIVKG DEIMAINGKI VTDYTLAEAD AALQKAWNQG GDWIDLVVAV CPPKEYDDEL TFF
    Purification
    SDS-PAGE
    Purity
    > 90 %
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    Discover our top product USH1C Protein
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.1-2 mg/mL
    Buffer
    20 mM Tris-HCl based buffer, pH 8.0
    Storage
    -80 °C,4 °C,-20 °C
    Storage Comment
    Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Target
    USH1C (Usher Syndrome 1C (Autosomal Recessive, Severe) (USH1C))
    Alternative Name
    USH1C (USH1C Products)
    Synonyms
    AIE-75 Protein, DFNB18 Protein, DFNB18A Protein, NY-CO-37 Protein, NY-CO-38 Protein, PDZ-45 Protein, PDZ-73 Protein, PDZ-73/NY-CO-38 Protein, PDZ73 Protein, PDZD7C Protein, ush1cpst Protein, 2010016F01Rik Protein, harmonin Protein, zgc:136806 Protein, ush1c Protein, USH1 protein network component harmonin Protein, harmonin Protein, Usher syndrome 1C Protein, USH1 protein network component harmonin L homeolog Protein, USH1C Protein, CpipJ_CPIJ012732 Protein, Ush1c Protein, ush1c Protein, ush1c.L Protein
    Background
    Required for normal development and maintenance of cochlear hair cell bundles. Anchoring/scaffolding protein that is a part of the functional network formed by USH1C, USH1G, CDH23 and MYO7A that mediates mechanotransduction in cochlear hair cells. Required for normal hearing .
    Molecular Weight
    76.3 kDa
    UniProt
    Q9Y6N9
    Pathways
    Sensory Perception of Sound
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