USH1C Protein (AA 1-533) (His-SUMO Tag)
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- Target See all USH1C Proteins
- USH1C (Usher Syndrome 1C (Autosomal Recessive, Severe) (USH1C))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-533
- Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This USH1C protein is labelled with His-SUMO Tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MDRKVAREFR HKVDFLIEND AEKDYLYDVL RMYHQTMDVA VLVGDLKLVI NEPSRLPLFD AIRPLIPLKH QVEYDQLTPR RSRKLKEVRL DRLHPEGLGL SVRGGLEFGC GLFISHLIKG GQADSVGLQV GDEIVRINGY SISSCTHEEV INLIRTKKTV SIKVRHIGLI PVKSSPDEPL TWQYVDQFVS ESGGVRGSLG SPGNRENKEK KVFISLVGSR GLGCSISSGP IQKPGIFISH VKPGSLSAEV GLEIGDQIVE VNGVDFSNLD HKEGRELFMT DRERLAEARQ RELQRQELLM QKRLAMESNK ILQEQQEMER QRRKEIAQKA AEENERYRKE MEQIVEEEEK FKKQWEEDWG SKEQLLLPKT ITAEVHPVPL RKPKYDQGVE PELEPADDLD GGTEEQGEQD FRKYEEGFDP YSMFTPEQIM GKDVRLLRIK KEGSLDLALE GGVDSPIGKV VVSAVYERGA AERHGGIVKG DEIMAINGKI VTDYTLAEAD AALQKAWNQG GDWIDLVVAV CPPKEYDDEL TFF
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product USH1C Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- USH1C (Usher Syndrome 1C (Autosomal Recessive, Severe) (USH1C))
- Alternative Name
- USH1C (USH1C Products)
- Synonyms
- AIE-75 Protein, DFNB18 Protein, DFNB18A Protein, NY-CO-37 Protein, NY-CO-38 Protein, PDZ-45 Protein, PDZ-73 Protein, PDZ-73/NY-CO-38 Protein, PDZ73 Protein, PDZD7C Protein, ush1cpst Protein, 2010016F01Rik Protein, harmonin Protein, zgc:136806 Protein, ush1c Protein, USH1 protein network component harmonin Protein, harmonin Protein, Usher syndrome 1C Protein, USH1 protein network component harmonin L homeolog Protein, USH1C Protein, CpipJ_CPIJ012732 Protein, Ush1c Protein, ush1c Protein, ush1c.L Protein
- Background
- Required for normal development and maintenance of cochlear hair cell bundles. Anchoring/scaffolding protein that is a part of the functional network formed by USH1C, USH1G, CDH23 and MYO7A that mediates mechanotransduction in cochlear hair cells. Required for normal hearing .
- Molecular Weight
- 76.3 kDa
- UniProt
- Q9Y6N9
- Pathways
- Sensory Perception of Sound
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