PPARG Protein (AA 209-477) (His tag)
-
- Target See all PPARG Proteins
- PPARG (Peroxisome Proliferator-Activated Receptor gamma (PPARG))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 209-477
-
Origin
- Human
-
Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This PPARG protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- PPARG, 209-477aa, Human, His tag, E.coli
- Purity
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product PPARG Protein
-
-
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1.0 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol 0.1M NaCl
- Storage
- 4 °C
-
- Target
- PPARG (Peroxisome Proliferator-Activated Receptor gamma (PPARG))
- Alternative Name
- PPARG (PPARG Products)
- Synonyms
- PPAR gamma Protein, PPARg2 Protein, PPARG Protein, Nr1c3 Protein, PPAR-gamma Protein, PPAR-gamma2 Protein, PPARgamma Protein, PPARgamma2 Protein, NR1C3 Protein, CIMT1 Protein, GLM1 Protein, PPARG1 Protein, PPARG2 Protein, xPPAR-gamma Protein, PPAR-GAMMA Protein, PPARGAMMA Protein, peroxisome proliferator-activated receptor gamma Protein, peroxisome proliferator activated receptor gamma Protein, peroxisome proliferator activated receptor gamma L homeolog Protein, PPARG Protein, Pparg Protein, pparg.L Protein
- Background
- PPARG, also known as Peroxisome proliferator-activated receptor gamma, is member of the nuclear hormone receptor subfamily of transcription factors. This protein regulates transcription of genes involved in Insulin action, adipocyte differentiation, lipid metabolism and inflammation. It is implicated in numerous diseases including obesity, diabetes, atherosclerosis and cancer. It also activators include prostanoids, fatty acids, thiazolidinediones and N-(2-benzoylphenyl) tyrosine analogues. PPARG may modulate macrophage functions such as proinflammatory activities, and stimulate oxidized low-density lipoprotein (x-LDL) uptake. Recombinant human PPARG protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: NR1C3, CIMT1, GLM1, NR1C3, PPARG1, PPARG2, PPARgamma, Peroxisome proliferator-activated receptor gamma. NCBI no.: NP_619725
- Molecular Weight
- 33.0kDa (290aa) confirmed by MALDI-TOF
- Pathways
- MAPK Signaling, Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, Regulation of Lipid Metabolism by PPARalpha, Positive Regulation of Endopeptidase Activity, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation
-