CBFB Protein (AA 1-182) (His tag)
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- Target See all CBFB Proteins
- CBFB (Core-Binding Factor, beta Subunit (CBFB))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-182
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This CBFB protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- CBFB, 1-182aa, Human, His tag, E.coli
- Purity
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product CBFB Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20 mM MES (pH 6.0) containing 0.1 mM PMSF, 10% Glycerol
- Storage
- 4 °C
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- Target
- CBFB (Core-Binding Factor, beta Subunit (CBFB))
- Alternative Name
- CBFB (CBFB Products)
- Synonyms
- PEBP2B Protein, Cbfb Protein, pebp2b Protein, Pebp2 Protein, CBFB Protein, unp1266 Protein, cbf-beta Protein, cbfbeta Protein, pea2-beta Protein, pebp2-beta Protein, AI893578 Protein, PEA2 Protein, PEBP2b Protein, Pebpb2 Protein, core-binding factor beta subunit Protein, core binding factor beta subunit Protein, core-binding factor, beta subunit Protein, core-binding factor, beta subunit S homeolog Protein, core binding factor beta Protein, CBFB Protein, Cbfb Protein, cbfb Protein, cbfb.S Protein
- Background
- CBFB, also known as PEBP2B, is the beta subunit of a heterodimeric core-binding transcription factor belonging to the PEBP2/CBF transcription factor family which master-regulates a host of genes specific to hematopoiesis (e.g., RUNX1) and osteogenesis (e.g., RUNX2). This protein is a non-DNA binding regulatory subunit and it allosterically enhances DNA binding by alpha subunit. Recombinant human CBFB protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: PEBP2B (polyomavirus enhancer binding protein b), PEA2, CBF-beta, Core-binding factor, beta subunit. NCBI no.: NP_001746
- Molecular Weight
- 23.6 kDa(202aa), confirmed by MALDI-TOF
- Pathways
- Regulation of Lipid Metabolism by PPARalpha
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