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AKR1C4 Protein (AA 1-323) (His tag)

AKR1C4 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS
Catalog No. ABIN667485
  • Target See all AKR1C4 Proteins
    AKR1C4 (Aldo-keto Reductase Family 1 Member C4 (AKR1C4))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-323
    Origin
    • 7
    • 1
    Human
    Source
    • 4
    • 1
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This AKR1C4 protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Characteristics
    AKR1C4, 1-323aa, Human, His tag, E.coli
    Purity
    > 90 % by SDS - PAGE
    Top Product
    Discover our top product AKR1C4 Protein
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1.0 mg/ml (determined by Bradford assay)
    Buffer
    Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 0.1M NaCl,1mM DTT
    Storage
    4 °C
  • Target
    AKR1C4 (Aldo-keto Reductase Family 1 Member C4 (AKR1C4))
    Alternative Name
    AKR1C4 (AKR1C4 Products)
    Synonyms
    3-alpha-HSD Protein, C11 Protein, CDR Protein, CHDR Protein, DD-4 Protein, DD4 Protein, HAKRA Protein, aldo-keto reductase family 1 member C4 Protein, AKR1C4 Protein
    Background
    AKR1C4 belongs to aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. It catalyzes the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. This enzyme catalyzes the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in liver. Recombinant human AKR1C4 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: Aldo-keto reductase family 1 member C4, DHEA-ST, DHEAS, HST, hSTa, ST2, ST2A1, ST2A3. NCBI no.: NP_001809
    Molecular Weight
    39.2 kDa(343aa), confirmed by MALDI-TOF
    Pathways
    Steroid Hormone Biosynthesis
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