AKR1C4 Protein (His tag)
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- Target See all AKR1C4 Proteins
- AKR1C4 (Aldo-keto Reductase Family 1 Member C4 (AKR1C4))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This AKR1C4 protein is labelled with His tag.
- Purpose
- Recombinant Human AKR1C4 Protein (His Tag)
- Sequence
- Met 1-Tyr323
- Characteristics
- Recombinant Human Aldo-Keto Reductase Family 1 Member C4 is produced by our E.coli expression system and the target gene encoding Met1-Tyr323 is expressed with a 6His tag at the N-terminus.
- Purity
- > 90 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product AKR1C4 Protein
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Aldo-keto Reductase Family 1 Member C4 (AKR1C4) (AA 1-343) protein (His tag)
AKR1C4 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Aldo-keto Reductase Family 1 Member C4 (AKR1C4) (AA 1-323) protein (GST tag)AKR1C4 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
Aldo-keto Reductase Family 1 Member C4 (AKR1C4) (AA 1-323) protein (Strep Tag)Crystallography grade AKR1C4 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB
Aldo-keto Reductase Family 1 Member C4 (AKR1C4) (AA 1-323) (Active) proteinAKR1C4 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS Active
Aldo-keto Reductase Family 1 Member C4 (AKR1C4) protein (Myc-DYKDDDDK Tag)AKR1C4 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Frozen, Liquid
- Buffer
- Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, pH 8.0.
- Storage
- -20 °C
- Storage Comment
- Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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- Target
- AKR1C4 (Aldo-keto Reductase Family 1 Member C4 (AKR1C4))
- Alternative Name
- AKR1C4 (AKR1C4 Products)
- Synonyms
- 3-alpha-HSD Protein, C11 Protein, CDR Protein, CHDR Protein, DD-4 Protein, DD4 Protein, HAKRA Protein, aldo-keto reductase family 1 member C4 Protein, AKR1C4 Protein
- Background
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Background: Aldo-Keto Reductase 1C4/AKR1C4 is a member of the aldo/keto reductase family that consists of more than 40 known enzymes and proteins. AKR1C4 has highly expressed in Liver. It can catalyzes the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in liver. AKR1C4 catalyzes the transformation of the potent androgen dihydrotestosterone (DHT) into the less active form, 5-α-Androstan-3-α,17-β-diol (3-α-diol). In addition, AKR1C4 also has some 20-α-Hydroxysteroid Dehydrogenase activity.
Synonym: Aldo-Keto Reductase Family 1 Member C4, 3-Alpha-HSD1, 3-Alpha-Hydroxysteroid Dehydrogenase Type I, Chlordecone Reductase, CDR, Dihydrodiol Dehydrogenase 4, DD-4, DD4, HAKRA, AKR1C4, CHDR
- Molecular Weight
- 39.3 kDa
- UniProt
- P17516
- Pathways
- Steroid Hormone Biosynthesis
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