LIN28A Protein (AA 42-209) (His tag)
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- Target See all LIN28A Proteins
- LIN28A (Lin-28 Homolog A (C. Elegans) (LIN28A))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 42-209
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This LIN28A protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- Lin28, 42-209 aa, Human, His-tag, E.coli
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product LIN28A Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol,0.1M NaCl
- Storage
- 4 °C
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- Target
- LIN28A (Lin-28 Homolog A (C. Elegans) (LIN28A))
- Alternative Name
- Lin28 (LIN28A Products)
- Synonyms
- CSDD1 Protein, LIN-28 Protein, LIN28 Protein, ZCCHC1 Protein, lin-28A Protein, AL024421 Protein, ENSMUSG00000070700 Protein, Gm10299 Protein, Lin-28 Protein, Lin28 Protein, Tex17 Protein, csdd1 Protein, lin-28 Protein, lin28 Protein, zcchc1 Protein, sb:cb650 Protein, zgc:55584 Protein, RGD1566408 Protein, lin-28 homolog A Protein, lin-28 homolog A (C. elegans) Protein, lin-28 homolog A S homeolog Protein, LIN28A Protein, Lin28a Protein, lin28a.S Protein, lin28a Protein
- Background
- Lin-28 acts as a 'translational enhancer', driving specific mRNAs to polysomes and thus increasing the efficiency of protein synthesis. It is marker of undifferentiated human embryonic stem cells and has been used to enhance the efficiency of the formation of induced pluripotent stem (iPS) cells from human fibroblasts. It has also been shown to bind to the let-7 pre-miRNA and block production of the mature let-7 microRNA in mouse embryonic stem cells. Recombinant Lin28 protein was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: CSDD1, FLJ12457, LIN-28, LIN28A, ZCCHC1, Zinc finger CCHC domain-containing protein 1 AL024421.Lin 28, Lin 28 homolog, Tex17, Lin28a, Lin 28 homolog (C, elegans), Lin 28 homolog A, RNA binding protein lin 28, Zinc finger CCHC domain containing protein 1. NCBI no.: NP_078950
- Molecular Weight
- 21.1 kDa (191aa), confirmed by MALDI-TOF.
- Pathways
- Stem Cell Maintenance
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