Aprataxin Protein (APTX) (AA 1-168) (His tag)
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- Target See all Aprataxin (APTX) Proteins
- Aprataxin (APTX)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-168
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This Aprataxin protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- Aprataxin, 1-168aa, Human, His tag, E. coli
- Purity
- > 95 % by SDS - PAGE
- Top Product
- Discover our top product APTX Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. 20mM Tris-HCl buffer (pH7.5) containing 20% glycerol, 100mM NaCl, 0.1mM PMSF
- Storage
- 4 °C
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- Target
- Aprataxin (APTX)
- Alternative Name
- Aprataxin (APTX Products)
- Synonyms
- aptx Protein, APTX Protein, LOC100284636 Protein, APRATAXIN-like Protein, T10O8.20 Protein, T10O8_20 Protein, AOA Protein, AOA1 Protein, AXA1 Protein, EAOH Protein, EOAHA Protein, FHA-HIT Protein, 2410016G21Rik Protein, AA388047 Protein, aprataxin Protein, FHA-HIT Protein, APRATAXIN-like protein Protein, aprataxin L homeolog Protein, aptx Protein, APTX Protein, CpipJ_CPIJ001673 Protein, LOC100284636 Protein, aptx.L Protein, Aptx Protein
- Background
- Aprataxin is a member of the histidine triad (HIT) superfamily, some of which have nucleotide-binding and diadenosine polyphosphate hydrolase activities. Aprataxin may play a role in single-stranded DNA repair. Mutations in the gene have been associated with neurological disorder known as ataxia oculomotor apraxia-1. Recombinant Aprataxin protein was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: APTX, AXA1, AOA, AOA 1, AOA1, Aprataxin homolog, Ataxia 1 early onset with hypoalbuminemia, Ataxia1 early onset with hypoalbuminemia, AXA 1, EAOH, EOAHA, FHA HIT, FLJ20157, MGC1072, Forkhead associated domain histidine triad like, Forkhead associated domain histidine triad like protein. NCBI no.: NP_778241
- Molecular Weight
- 23.9kDa (205aa), confirmed by MALDI-TOF.
- Pathways
- DNA Damage Repair, Chromatin Binding
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