STAT1 Protein (AA 1-712) (His tag)
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- Target See all STAT1 Proteins
- STAT1 (Signal Transducer and Activator of Transcription 1, 91kDa (STAT1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-712
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This STAT1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- STAT1, 1-712aa, Human, His tag, E.coli
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product STAT1 Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 0.1M Nacl, 1mM DTT, 10% glycerol
- Storage
- 4 °C
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- Target
- STAT1 (Signal Transducer and Activator of Transcription 1, 91kDa (STAT1))
- Alternative Name
- STAT1 (STAT1 Products)
- Synonyms
- CANDF7 Protein, ISGF-3 Protein, STAT91 Protein, 2010005J02Rik Protein, AA408197 Protein, XStat1 Protein, STAT4 Protein, DD6G4-4 Protein, STAT Protein, STAT1 Protein, dZ182H3.3 Protein, si:by134g18.2 Protein, si:by51f19.1 Protein, si:dz182h3.3 Protein, si:dz199m19.1 Protein, si:dz73o4.2 Protein, stat1 Protein, signal transducer and activator of transcription 1 Protein, signal transducer and activator of transcription 1 L homeolog Protein, signal transducer and activator of transcription 1, 91kDa Protein, signal transducer and activator of transcription 4 Protein, signal transducer and activator of transcription 1a Protein, STAT1 Protein, Stat1 Protein, stat1.L Protein, stat4 Protein, stat1a Protein
- Background
- STAT1, also known as STAT91, is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. STAT1 is activated by peptide hormones, growth factors and cytokines, particularly cytokines of the interferon family. Recombinant human STAT1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: ISGF-3, STAT91, Transcription factor ISGF-3 components p91/p84, Signal transducer and activator of transcription 1, 91kDa. NCBI no.: NP_009330
- Molecular Weight
- 85.2 kDa (732aa), confirmed by MALDI-TOF
- Pathways
- JAK-STAT Signaling, RTK Signaling, Interferon-gamma Pathway, Response to Growth Hormone Stimulus, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Hepatitis C, CXCR4-mediated Signaling Events
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