TWF1 Protein (AA 1-252) (His tag)
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- Target See all TWF1 Proteins
- TWF1 (Twinfilin, Actin-Binding Protein 1 (TWF1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-252
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This TWF1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Characteristics
- TWF1, 1-252aa, Human, His tag, E.coli
- Purity
- > 80 % by SDS - PAGE
- Top Product
- Discover our top product TWF1 Protein
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. 20mM Tris-HCl buffer (pH8.0) containing 40% glycerol, 0.15M NaCl, 1mM DTT
- Storage
- 4 °C
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- Target
- TWF1 (Twinfilin, Actin-Binding Protein 1 (TWF1))
- Alternative Name
- TWF1 (TWF1 Products)
- Synonyms
- A6 Protein, PTK9 Protein, Ptk9 Protein, twinfilin Protein, ptk9 Protein, twf1 Protein, wu:fd02b03 Protein, zgc:65922 Protein, DKFZp469O1925 Protein, CG3771 Protein, Dmel\\CG3771 Protein, EG:9D2.3 Protein, zgc:92472 Protein, twinfilin actin binding protein 1 Protein, twinfilin actin-binding protein 1a Protein, twinfilin actin binding protein 1 S homeolog Protein, twinfilin-1 Protein, hypothetical protein Protein, Twinfilin-1 Protein, twinfilin actin-binding protein 1 Protein, CG3771 gene product from transcript CG3771-RC Protein, twinfilin actin-binding protein 1b Protein, TWF1 Protein, Twf1 Protein, twf1a Protein, twf1.S Protein, PTRG_09288 Protein, PGTG_01788 Protein, Tsp_02530 Protein, twf1 Protein, a6 Protein, twf1b Protein
- Background
- TWF1 is a ubiquitous actin-monomer-binding protein that is composed of two ADF-homology domains. It forms a 1:1 complex with ADP-actin-monomers, inhibits nucleotide exchange on actin monomers and prevents assembly of the monomer into filaments. This protein composed of two ADF/cofilin-like (ADF-H) domains connected by a short linker region and followed by a C-terminal tail of 20 residues. The two ADF-H domains are 20% homologous to ADF/cofilin and to each other. Recombinant human TWF1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography. Synonyms: Twinfilin-1, PTK9. NCBI no.: AAH22344
- Molecular Weight
- 31.5 kDa (277aa) confirmed by MALDI-TOF
- Pathways
- Regulation of Actin Filament Polymerization, Maintenance of Protein Location
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