TWF1 Protein (GST tag,His tag)
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- Target See all TWF1 Proteins
- TWF1 (Twinfilin, Actin-Binding Protein 1 (TWF1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This TWF1 protein is labelled with GST tag,His tag.
- Purpose
- Recombinant Human TWF1/Twinfilin-1 Protein (His & GST Tag)
- Sequence
- Met 1-Asp 252
- Characteristics
- A DNA sequence encoding the human TWF1 isoform 4 (Q12792-4) (Met 1-Asp 252) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.
- Purity
- > 84 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product TWF1 Protein
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Twinfilin, Actin-Binding Protein 1 (TWF1) (AA 100-350) protein (His tag)
TWF1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Twinfilin, Actin-Binding Protein 1 (TWF1) (AA 1-384) protein (GST tag)TWF1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Twinfilin, Actin-Binding Protein 1 (TWF1) (AA 80-252) protein (GST tag)TWF1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Twinfilin, Actin-Binding Protein 1 (TWF1) (AA 2-350) protein (His tag)Crystallography grade TWF1 Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile 50 mM Tris, 500 mM NaCl, pH 8.0
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- TWF1 (Twinfilin, Actin-Binding Protein 1 (TWF1))
- Alternative Name
- TWF1/Twinfilin-1 (TWF1 Products)
- Synonyms
- A6 Protein, PTK9 Protein, Ptk9 Protein, twinfilin Protein, ptk9 Protein, twf1 Protein, wu:fd02b03 Protein, zgc:65922 Protein, DKFZp469O1925 Protein, CG3771 Protein, Dmel\\CG3771 Protein, EG:9D2.3 Protein, zgc:92472 Protein, twinfilin actin binding protein 1 Protein, twinfilin actin-binding protein 1a Protein, twinfilin actin binding protein 1 S homeolog Protein, twinfilin-1 Protein, hypothetical protein Protein, Twinfilin-1 Protein, twinfilin actin-binding protein 1 Protein, CG3771 gene product from transcript CG3771-RC Protein, twinfilin actin-binding protein 1b Protein, TWF1 Protein, Twf1 Protein, twf1a Protein, twf1.S Protein, PTRG_09288 Protein, PGTG_01788 Protein, Tsp_02530 Protein, twf1 Protein, a6 Protein, twf1b Protein
- Background
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Background: Twinfilin-1; also known as Protein A6; Protein tyrosine kinase 9; TWF1 and PTK9; is a cytoplasm protein which belongs to the actin-binding proteins ADF family and Twinfilin subfamily. Twinfilin-1 (TWF1 / PTK9 ) is a highly conserved actin monomer-binding protein that regulates cytoskeletal dynamics in organisms from yeast to mammals. In addition to the mammalian twinfilin-1; a second protein with approximately 65% sequence identity to twinfilin-1 exists in mouse and humans. TWF1 / PTK9 is expressed at high levels in the colon; testis; ovary; prostate and lung. It is expressed at lower levels in the brain; bladder and heart. It is not detected in liver. TWF1 / PTK9 is an actin-binding protein involved in motile and morphological processes. It inhibits actin polymerization; likely by sequestering G-actin. By capping the barbed ends of filaments; it also regulates motility. TWF1 / PTK9 seems to play an important role in clathrin-mediated endocytosis and distribution of endocytic organelles.
Synonym: A6;MGC23788;MGC41876;PTK9
- Molecular Weight
- 57 kDa
- Pathways
- Regulation of Actin Filament Polymerization, Maintenance of Protein Location
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