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EGF Protein

EGF Origin: Mouse Host: Escherichia coli (E. coli) Recombinant 97 % by SDS-PAGE and HPLC analyses. Active
Catalog No. ABIN871826
  • Target See all EGF Proteins
    EGF (Epidermal Growth Factor (EGF))
    Protein Type
    Recombinant
    Biological Activity
    Active
    Origin
    • 29
    • 17
    • 9
    • 4
    • 3
    • 1
    Mouse
    Source
    • 34
    • 9
    • 8
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Sequence
    NSYPGCPSSY DGYCLNGGVC MHIESLDSYT CNCVIGYSGD RCQTRDLRWW ELR
    Purity
    97 % by SDS-PAGE and HPLC analyses.
    Sterility
    0.2 μm filtered
    Endotoxin Level
    Less than 1EU/µg of rmEGF as determined by LAL method.
    Top Product
    Discover our top product EGF Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at < -20° C. Further dilutions should be made in appropriate buffered solutions.
    Storage
    4 °C/-20 °C
  • Target
    EGF (Epidermal Growth Factor (EGF))
    Alternative Name
    EGF (EGF Products)
    Synonyms
    HOMG4 Protein, URG Protein, AI790464 Protein, CEGF Protein, epidermal growth factor Protein, pro-epidermal growth factor Protein, EGF Protein, egf Protein, CpipJ_CPIJ020278 Protein, Egf Protein
    Background
    EGF was originally discovered in crude preparations of nerve growth factor prepared from mouse submaxillary glands as an activity that induced early eyelid opening, incisor eruption, hair growth inhibition, and stunting of growth when injected into newborn mice. EGF is a potent growth factor that stimulates the proliferation of various epidermal and epithelial cells. Additionally, EGF has been shown to inhibit gastric secretion, and to be involved in wound healing. EGF signals through a receptor known as c-erbB, which is a class I tyrosine kinase receptor. This receptor also binds with TGF-alpha and VGF (vaccinia virus growth factor).
    Pathways
    NF-kappaB Signaling, RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Protein targeting to Nucleus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation
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