Retinoblastoma Binding Protein 8 antibody (AA 620-897)
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- Target See all Retinoblastoma Binding Protein 8 (RBBP8) Antibodies
- Retinoblastoma Binding Protein 8 (RBBP8)
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Binding Specificity
- AA 620-897
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This Retinoblastoma Binding Protein 8 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF), Immunocytochemistry (ICC)
- Purification
- Protein A Chromatography
- Immunogen
- This CtIP antibody was raised against a recombinant protein corresponding to amino acid residues 620-897 of human CtIP.
- Clone
- 14-1
- Isotype
- IgG1
- Top Product
- Discover our top product RBBP8 Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Concentration
- 1 μg/μL
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
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Avoid repeated freeze/thaw cycles and keep on ice when not in storage.
- Storage
- -20 °C
- Storage Comment
- Antibodies in solution can be stored at -20 °C for 2 years.
- Expiry Date
- 6 months
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Tetratricopeptide repeat factor XAB2 mediates the end resection step of homologous recombination." in: Nucleic acids research, Vol. 44, Issue 12, pp. 5702-16, (2016) (PubMed).
: "Impaired 53BP1/RIF1 DSB mediated end-protection stimulates CtIP-dependent end resection and switches the repair to PARP1-dependent end joining in G1." in: Oncotarget, Vol. 7, Issue 36, pp. 57679-57693, (2016) (PubMed).
: "Quantitation of DNA double-strand break resection intermediates in human cells." in: Nucleic acids research, Vol. 42, Issue 3, pp. e19, (2014) (PubMed).
: "Catalytic and noncatalytic roles of the CtIP endonuclease in double-strand break end resection." in: Molecular cell, Vol. 54, Issue 6, pp. 1022-33, (2014) (PubMed).
: "An essential role for CtIP in chromosomal translocation formation through an alternative end-joining pathway." in: Nature structural & molecular biology, Vol. 18, Issue 1, pp. 80-4, (2011) (PubMed).
: "BRCA1 ubiquitinates its phosphorylation-dependent binding partner CtIP." in: Genes & development, Vol. 20, Issue 13, pp. 1721-6, (2006) (PubMed).
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Tetratricopeptide repeat factor XAB2 mediates the end resection step of homologous recombination." in: Nucleic acids research, Vol. 44, Issue 12, pp. 5702-16, (2016) (PubMed).
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- Target
- Retinoblastoma Binding Protein 8 (RBBP8)
- Alternative Name
- CtIP (RBBP8 Products)
- Synonyms
- COM1 antibody, CTIP antibody, JWDS antibody, RIM antibody, SAE2 antibody, SCKL2 antibody, 9930104E21Rik antibody, CtIP antibody, RBBP-8 antibody, RGD1308872 antibody, RBBP8 antibody, DKFZp469K0714 antibody, RB binding protein 8, endonuclease antibody, retinoblastoma binding protein 8, endonuclease antibody, retinoblastoma binding protein 8 L homeolog antibody, retinoblastoma binding protein 8 antibody, RBBP8 antibody, Rbbp8 antibody, rbbp8.L antibody, rbbp8 antibody
- Molecular Weight
- 120 kDa
- Gene ID
- 5932
- Pathways
- Cell Division Cycle, DNA Damage Repair
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