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Deleted in Colorectal Carcinoma ELISA Kits (DCC)
On are 3 Deleted in Colorectal Carcinoma (DCC) ELISA Kits from 2 different suppliers available. Additionally we are shipping DCC Antibodies (91) and DCC Proteins (8) and many more products for this protein. A total of 108 DCC products are currently listed.
Abcc1b, C030036D22Rik, CRC18, CRCR1, DCC, dcca-A, dyscalc, Dyscalc1, Igdcc1, MRMV1, Mrp6, xdcc, XDCCa, zdcc
list all ELISA KIts Gene Name GeneID UniProt
DCC 27421 Q9R1S7
DCC 1630 P43146
Rat DCC DCC 25311 Q63155

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Mouse (Murine) Deleted in Colorectal Carcinoma (DCC) interaction partners

  1. Results suggest that Dcc plays an important role in the developmental formation of peripheral and central auditory circuits, and its mutation may contribute to sensorineural hearing loss.

  2. dcc haploinsufficient mice acquire intracranial self-stimulation behavior and that the parameters of the stimulation are comparable to those observed in wild-type littermates; reduced expression of dcc may dampen the abuse potential of cocaine

  3. Identified the Dcc gene as a novel downstream target of spontaneous calcium activity involved in axon growth.

  4. bisphosphonates may be helpful for prevention of mineral deposits in Pseudoxanthoma elasticum and generalized arterial calcification of infancy caused by mutations in the ABCC6 (show ABCC6 ELISA Kits) gene.

  5. suggest that DCC signaling functions through NCK1 and NCK2 and that both proteins are necessary for the establishment of normal spinal circuits necessary for gait

  6. Results suggest that down syndrome cell adhesion molecule (show DSCAM ELISA Kits) collaborates with deleted in colorectal cancer to regulate microtubule dynamics via direct binding to dynamic TUBB3 (show TUBB3 ELISA Kits) in Netrin-1 (show NTN1 ELISA Kits)-induced axon branching.

  7. In a mouse model of CKD, ABCC6 (show ABCC6 ELISA Kits) protein expression was decreased in liver and kidney, however mRNA levels were unchanged.

  8. Data indicate the roles of Slit1 (show SLIT1 ELISA Kits)/Robo1 (show ROBO1 ELISA Kits) and Netrin1/DCC signals in positioning motor neuron cell bodies.

  9. These data demonstrate robust cardioprotective effect of netrin-1 (show NTN1 ELISA Kits) in vivo, as shown by reduced infarct size and improved cardiac function mediated by netrin-1 (show NTN1 ELISA Kits) receptor DCC.

  10. Unc5C (show Unc5c ELISA Kits) and DCC act downstream of Ctip2 (show BCL11B ELISA Kits) and Satb2 (show SATB2 ELISA Kits) and contribute to corpus callosum formation.

Zebrafish Deleted in Colorectal Carcinoma (DCC) interaction partners

  1. Schwann cell and dcc-mediated guidance are critical early during regeneration to direct growth cones across the transection gap and onto their original axonal trajectory.

  2. in dcc mutants, turns on the inappropriate side of the body are caused by aberrant ipsilateral axonal projections

  3. Dcc-Netrin1 and roundabout2 (Robo2)-Slit coordinate axonal projection choices of neurons in the developing forebrain.

  4. Dcc regulates polarized axon initiation and asymmetric outgrowth of forebrain neurons

  5. dcc may play roles not only in axon guidance, but in morphogenesis and functioning of these organs as well

  6. First evidence that Netrin/DCC axon guidance molecules act in dendrites in a vertebrate system.

Xenopus laevis Deleted in Colorectal Carcinoma (DCC) interaction partners

  1. ESCRT-II (show VPS28 ELISA Kits)-mediated endocytic pathway regulates both DCC and local protein synthesis.

Human Deleted in Colorectal Carcinoma (DCC) interaction partners

  1. Identified DCC mutations in four families.

  2. DCC polymorphism maybe responsible for successful treatment of patients with hydrochlorothiazide . diagnosed with hypertension.

  3. Deleted in colorectal cancer (DCC) confers susceptibility to depression-like behaviors in humans and mice and Is regulated by miR (show MLXIP ELISA Kits)-218. By regulating DCC, miR (show MLXIP ELISA Kits)-218 may be a switch of susceptibility versus resilience to stress-related disorders.

  4. DCC/18q and ERBB2 (show ERBB2 ELISA Kits)/17q gene copy number variations are associated with disease-free survival in microsatellite stable colon cancer

  5. Allelic and genotypic frequencies of the DCC polymorphism rs2229080 were nominally associated with schizophrenia.

  6. Results of APC and DCC LOH, KRAS and microsatellite instability indicate our colorectal cancer cases were typical of sporadic cancers following the 'chromosomal instability' pathway.

  7. The study identified DCC as a differentially expressed gene and clustered meningiomas into DCC low expression (3 grade I and 3 grade II tumors), DCC medium expression (2 grade I and 1 grade II tumors), and DCC high expression (5 grade I tumors) groups.

  8. Data suggest that, in response to netrin-1 (show NTN1 ELISA Kits)/netrin receptor (DCC) signaling, p120RasGAP (show RASA1 ELISA Kits) is recruited to growth cones and supports axon outgrowth; p120RasGAP (show RASA1 ELISA Kits) Src (show SRC ELISA Kits) homology 2 domains exhibit scaffolding properties sufficient to support axon outgrowth.

  9. By analyzing multiple myeloma-derived cell lines and patient-derived primary CD138 (show SDC1 ELISA Kits)-positive plasma cells ... authors show for the first time that transcriptional dysregulation of DCC is involved in the progression of plasma cell malignancy.

  10. the transfected DCC gene can suppress cell proliferation and lead to downregulation of CEA (show CEACAM5 ELISA Kits) expression in SW1116 cells.

DCC Antigen Profile

Antigen Summary

This gene encodes a netrin 1 receptor. The transmembrane protein is a member of the immunoglobulin superfamily of cell adhesion molecules, and mediates axon guidance of neuronal growth cones towards sources of netrin 1 ligand. The cytoplasmic tail interacts with the tyrosine kinases Src and focal adhesion kinase (FAK, also known as PTK2) to mediate axon attraction. The protein partially localizes to lipid rafts, and induces apoptosis in the absence of ligand. The protein functions as a tumor suppressor, and is frequently mutated or downregulated in colorectal cancer and esophageal carcinoma.

Alternative names and synonyms associated with DCC

  • ATP-binding cassette, sub-family C (CFTR/MRP), member 6 (Abcc6) Elisa Kit
  • deleted in colorectal carcinoma (DCC) Elisa Kit
  • deleted in colorectal carcinoma (dcc) Elisa Kit
  • deleted in colorectal carcinoma (Dcc) Elisa Kit
  • Abcc1b Elisa Kit
  • C030036D22Rik Elisa Kit
  • CRC18 Elisa Kit
  • CRCR1 Elisa Kit
  • DCC Elisa Kit
  • dcca-A Elisa Kit
  • dyscalc Elisa Kit
  • Dyscalc1 Elisa Kit
  • Igdcc1 Elisa Kit
  • MRMV1 Elisa Kit
  • Mrp6 Elisa Kit
  • xdcc Elisa Kit
  • XDCCa Elisa Kit
  • zdcc Elisa Kit

Protein level used designations for DCC

ATP-binding cassette sub-family C member 6 , ATP-binding cassette, sub-family C, member 6 , multidrug resistance-associated protein 6 , multidrug resistance-associated protein-6 , deleted in colorectal carcinoma , netrin receptor DCC , deleted in colorectal cancer , deleted in colorectal cancer tumor suppressor , netrin receptor DCC-like , colorectal cancer suppressor , colorectal tumor suppressor , deleted in colorectal cancer protein , immunoglobulin superfamily DCC subclass member 1 , immunoglobulin superfamily, DCC subclass, member 1 , tumor suppressor protein DCC

27421 Mus musculus
455425 Pan troglodytes
483976 Canis lupus familiaris
537176 Bos taurus
569360 Danio rerio
693352 Macaca mulatta
100054013 Equus caballus
378529 Xenopus laevis
100442362 Pongo abelii
100410745 Callithrix jacchus
100556072 Anolis carolinensis
100583619 Nomascus leucogenys
1630 Homo sapiens
13176 Mus musculus
25311 Rattus norvegicus
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