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anti-Mouse (Murine) Tumor Protein p73 Antibodies:
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Human Monoclonal Tumor Protein p73 Primary Antibody for ChIP, CyTOF - ABIN4343232
Shimodaira, Yoshioka-Yamashita, Kolodner, Wang: Interaction of mismatch repair protein PMS2 and the p53-related transcription factor p73 in apoptosis response to cisplatin. in Proceedings of the National Academy of Sciences of the United States of America 2003
Show all 49 Pubmed References
Human Monoclonal Tumor Protein p73 Primary Antibody for ChIP, ICC - ABIN252619
Costanzo, Merlo, Pediconi, Fulco, Sartorelli, Cole, Fontemaggi, Fanciulli, Schiltz, Blandino, Balsano, Levrero: DNA damage-dependent acetylation of p73 dictates the selective activation of apoptotic target genes. in Molecular cell 2002
Show all 27 Pubmed References
Human Polyclonal Tumor Protein p73 Primary Antibody for IHC (p), IP - ABIN151880
Levy, Adamovich, Reuven, Shaul: The Yes-associated protein 1 stabilizes p73 by preventing Itch-mediated ubiquitination of p73. in Cell death and differentiation 2007
Show all 13 Pubmed References
Human Monoclonal Tumor Protein p73 Primary Antibody for IP, WB - ABIN967629
Jost, Marin, Kaelin: p73 is a simian [correction of human] p53-related protein that can induce apoptosis. in Nature 1997
Show all 5 Pubmed References
Human Monoclonal Tumor Protein p73 Primary Antibody for IP, WB - ABIN967628
Zhu, Jiang, Zhou, Chen: The potential tumor suppressor p73 differentially regulates cellular p53 target genes. in Cancer research 1998
Show all 5 Pubmed References
Human Monoclonal Tumor Protein p73 Primary Antibody for IP, WB - ABIN967630
De Laurenzi, Costanzo, Barcaroli, Terrinoni, Falco, Annicchiarico-Petruzzelli, Levrero, Melino: Two new p73 splice variants, gamma and delta, with different transcriptional activity. in The Journal of experimental medicine 1998
Show all 5 Pubmed References
Human Monoclonal Tumor Protein p73 Primary Antibody for WB - ABIN252620
Shao, Tanaka, Gribi, Yu: Thioredoxin-related regulation of NO/NOS activities. in Annals of the New York Academy of Sciences 2002
Human Monoclonal Tumor Protein p73 Primary Antibody for GS, ICC - ABIN269466
King, Reddi, Ponnamperuma, Gerdes, Weinberg: Dysregulated ΔNp63α negatively regulates the maspin promoter in keratinocytes via blocking endogenous p73 binding. in Molecular carcinogenesis 2014
Human Polyclonal Tumor Protein p73 Primary Antibody for IHC - ABIN966779
Yuan, Shioya, Ishiko, Sun, Gu, Huang, Lu, Kharbanda, Weichselbaum, Kufe: p73 is regulated by tyrosine kinase c-Abl in the apoptotic response to DNA damage. in Nature 1999
New function of p73 (show ARHGAP24 Antibodies), independent of p53 (show TP53 Antibodies), in the neurogenic architecture of the SVZ of rodent brain.
these results therefore highlight an unanticipated role for p53 (show TP53 Antibodies) family proteins in a regulatory network that integrates essential Wnt (show WNT2 Antibodies)-Tcf (show HNF4A Antibodies) and nodal-Smad (show SMAD1 Antibodies) inputs.
TAp73 as necessary and sufficient for basal body docking, axonemal extension, and motility during the differentiation of Motile multiciliated cell progenitors.
p73 (show ARHGAP24 Antibodies) drives multiciliogenesis, both through transcriptional activation of a master ciliogenesis transcription factor FoxJ1 (show FOXJ1 Antibodies) and through regulation of multiple genes central to ciliogenesis.
The p73 (show ARHGAP24 Antibodies) acts as a critical regulator of multiciliogenesis in its capacity as a sequence-specific transcription factor, through genomic binding and regulation of genes.
Data show that the Mdm4 (show MDM4 Antibodies)-p73 (show ARHGAP24 Antibodies) axis cannot override the dominant role of p53 (show TP53 Antibodies) in development and tumorigenesis and that Mdm4 (show MDM4 Antibodies) and p73 (show ARHGAP24 Antibodies) interaction during development and tumorigenesis suggests new insight into the role of p53 (show TP53 Antibodies) family members.
In vivo inhibition of both p63 (show CKAP4 Antibodies) and p73 (show ARHGAP24 Antibodies) in combination accelerates tumor regression and increases survival of p53 (show TP53 Antibodies)-deficient mice.
Results indicate that p73 (show ARHGAP24 Antibodies) regulates basal and starvation-induced fuel metabolism in the liver, a finding that is likely to be highly relevant for metabolism-associated disorders, such as diabetes and cancer.
MDM2 (show MDM2 Antibodies) mediates p73 (show ARHGAP24 Antibodies) ubiquitination
p73 (show ARHGAP24 Antibodies) is required for endothelial cell differentiation, migration and the formation of vascular networks regulating VEGF (show VEGFA Antibodies) and TGFbeta (show TGFB1 Antibodies) signaling
The reduction of tumor protein p63 (show TP63 Antibodies) and tumor protein p73 isoforms, rather than alteration of DeltaN isoform expression, exerted a significant functional repercussion on cell death and proliferation in hepatitis B virus -expressing HepB cells.
p73 is epigenetically silenced in chondrosarcoma due to promoter methylation, which suggests the utility of p73 methylation as a biomarker.
A considerable number of lymphoma patients lacked the expression of either or both isoforms, while all lymphoid leukemia patients expressed both isoforms. The expression pattern differences of p73 isoforms may reflect differences in the biology of these malignancies.
TAp73beta upregulates pro-IL-1beta (show IL1B Antibodies) mRNA and processed IL-1beta (show IL1B Antibodies) protein. In addition, analysis of breast and lung cancer patient cohorts demonstrated that interaction between p73 and IL-1beta (show IL1B Antibodies) predicts a negative survival outcome in these cancers.
analysis of how trifluoroethanol induces a conformational transition in the C-terminal sterile alpha motif (SAM (show TTN Antibodies)) of human p73
The findings of this study suggested that the polymorphism G4C14-to-A4T14 in p73 gene might be associated with severe spermatogenesis impairment and could affect the susceptibility to male infertility with severe spermatogenesis impairment in Chinese population.
Authors confirmed that miR (show MLXIP Antibodies)-200a could directly bind to TP73-AS1 and the 3'UTR (show UTS2R Antibodies) of HMGB1 (show HMGB1 Antibodies); TP73-AS1 competed with HMGB1 (show HMGB1 Antibodies) for miR (show MLXIP Antibodies)-200a binding.
The p73 gene may play a role as a tumor suppressor in the colorectal cancer progression.
TP73 expression in cervical cancer was significantly higher than that in normal cervical squamous epithelium (meta-analysis)
Expression of XAF1 (show XAF1 Antibodies) and TAp73 was also upregulated in casticin-treated T24 cells.
This gene encodes a member of the p53 family of transcription factors involved in cellular responses to stress and development. It maps to a region on chromosome 1p36 that is frequently deleted in neuroblastoma and other tumors, and thought to contain multiple tumor suppressor genes. The demonstration that this gene is monoallelically expressed (likely from the maternal allele), supports the notion that it is a candidate gene for neuroblastoma. Many transcript variants resulting from alternative splicing and/or use of alternate promoters have been found for this gene, but the biological validity and the full-length nature of some variants have not been determined.
tumor protein p73
, tumor protein p73-like
, p53-like transcription factor
, p53-related protein
, transformation related protein 73