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anti-Human Poliovirus Receptor Antibodies:
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Human Monoclonal Poliovirus Receptor Primary Antibody for CyTOF, FACS - ABIN4900023
Perier, Fregni, Wittnebel, Gad, Allard, Gervois, Escudier, Azzarone, Caignard: Mutations of the von Hippel-Lindau gene confer increased susceptibility to natural killer cells of clear-cell renal cell carcinoma. in Oncogene 2011
Show all 5 Pubmed References
Human Polyclonal Poliovirus Receptor Primary Antibody for WB - ABIN1881709
Nakai, Maniwa, Tanaka, Nishio, Yoshimura, Okita, Ohbayashi, Satoh, Ogita, Takai, Hayashi: Overexpression of Necl-5 correlates with unfavorable prognosis in patients with lung adenocarcinoma. in Cancer science 2010
Show all 3 Pubmed References
Human Monoclonal Poliovirus Receptor Primary Antibody for FACS - ABIN4897066
Parrish, Scott, Migneco, Scott, Steele, Ilett, West, Hall, Selby, Buchanan, Varghese, Cragg, Coffey, Hillmen, Melcher, Errington-Mais: Oncolytic reovirus enhances rituximab-mediated antibody-dependent cellular cytotoxicity against chronic lymphocytic leukaemia. in Leukemia 2015
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Human Monoclonal Poliovirus Receptor Primary Antibody for FACS - ABIN2478636
Bitoun, Timsit, Trang, Benady: A new look at the management of the oculo-mandibulo-facial syndrome. in Ophthalmic paediatrics and genetics 1992
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Human Monoclonal Poliovirus Receptor Primary Antibody for Func, FACS - ABIN2478639
Fuchs, Cella, Giurisato, Shaw, Colonna: Cutting edge: CD96 (tactile) promotes NK cell-target cell adhesion by interacting with the poliovirus receptor (CD155). in Journal of immunology (Baltimore, Md. : 1950) 2004
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Human Polyclonal Poliovirus Receptor Primary Antibody for WB - ABIN519547
Márquez, Kohli, Arteta, Chang, Li, Goldblatt, Vidal-Vanaclocha: Identification of hepatic microvascular adhesion-related genes of human colon cancer cells using random homozygous gene perturbation. in International journal of cancer. Journal international du cancer 2013
Studies showed that CD155 was frequently overexpressed in human malignant tumors. Its overexpression promotes tumor cell invasion and migration, and is associated with tumor progression. [review]
soluble CD226 (show CD226 Antibodies) elevated in sera of CTCL (show TSPYL2 Antibodies) patients would be important for tumor immunity by interacting with CD155 on tumor cells.
data reveal that MICA (show MICA Antibodies) and PVR are directly regulated by human cytomegalovirus immediate early (show JUN Antibodies) proteins, and this may be crucial for the onset of an early host antiviral response
The SNP detection assay was successfully developed for identification of Ala67Thr polymorphism in human PVR/CD155 gene. The SNP assay will be useful for large scale screening of DNA samples.
implying that TIGIT (show TIGIT Antibodies) exerts immunosuppressive effects by competing with DNAM-1 (show CD226 Antibodies) for the same ligand, CD155
The present study provides evidence that regulation of the PVR/CD155 DNAM-1 (show CD226 Antibodies) ligand expression by nitric oxide may represent an additional immune-mediated mechanism and supports the anti-myeloma activity of nitric oxide donors.
Our findings suggest that loss of CD155 expression may play an important role in the immune escape of HCC (show FAM126A Antibodies) cells and thus CD155 may serve as a prognostic marker as well as a potential therapeutic target for HCC (show FAM126A Antibodies).
CD155 may play a critical role through both immunological and non-immuno logical mechanisms in pancreatic cancer and may be a therapeutic target for this intractable malignancy.
CD155 (PVR/Necl5) mediates a costimulatory signal in CD4 (show CD4 Antibodies)+ T cells and regulates allergic inflammation.
The cell-surface receptor (Pvr) catalyzes a large structural change in the poliovirus that exposes membrane-binding protein chains.
Data show that CD155 protein/CD226 antigen (show CD226 Antibodies) mainly mediates the interaction between NK cells and leukemic cells in acute myeloid leukemia (show BCL11A Antibodies). To investigate the interaction between leukemic cells
absence of either CD155 or CD226 (show CD226 Antibodies) in BALB/c mice causes a profound shift in the Natural Killer T-Cells subtype composition in thymus, expanding the frequency and numbers of iNKT1 cells at the expense of iNKT2 cells, as well as iNKT17 cells.
Results suggest that modulation of the expression of receptors and CD112 (show PVRL2 Antibodies) compensates for CD155 deficiency in immune surveillance against methylcholanthrene-induced tumors.
Sertoli cells recognize the excess cytoplasm of elongated spermatids through the PVR (show PVRL2 Antibodies)-CEACAM2-L (show CEACAM2 Antibodies) interaction in mouse testis
TIGIT (show TIGIT Antibodies)/PVR (show PVRL2 Antibodies) ligation signaling mediates suppression of IFN-gamma (show IFNG Antibodies) production via the NF-kappaB (show NFKB1 Antibodies) pathway.
Our data suggest that CD155 regulates T(h)2 differentiation
These observations establish a firm link between the functions of CD155 and CD226 (show CD226 Antibodies) in several T cell differentiation steps.
Necl-5/poliovirus receptor interacts with VEGFR2 (show KDR Antibodies) and regulates VEGF (show VEGFA Antibodies)-induced angiogenesis.
The TLR3 (show TLR3 Antibodies)-TRIF (show RNF138 Antibodies) mediated antiviral response is important for protection against poliovirus infection in poliovirus receptor transgenic mice.
The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene.
, nectin-like 5
, nectin-like protein 5
, tumor-associated antigen 1
, tumor-associated glycoprotein pE4