Poliovirus Receptor antibody

Catalog No. ABIN7261702

Product Details anti-Poliovirus Receptor Antibody

Target: Poliovirus Receptor (PVR)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Poliovirus Receptor antibody is un-conjugated

Application: Western Blotting (WB)

Characteristics: Polyclonal Antibody

Purification: Affinity purification

Immunogen: Recombinant fusion protein of human CD155/PVR (NP_006496.4).

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Poliovirus Receptor

Target: Poliovirus Receptor (PVR)

Alternative Name: CD155/PVR (PVR Products)

Synonyms: PVR antibody, CD155 antibody, HVED antibody, NECL5 antibody, Necl-5 antibody, PVS antibody, TAGE4 antibody, 3830421F03Rik antibody, D7Ertd458e antibody, Taa1 antibody, Tage4 antibody, mE4 antibody, necl-5 antibody, poliovirus receptor antibody, PVR antibody, Pvr antibody

Background: The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene.

Molecular Weight:

Observed_MW: 70 kDa

Calculated_MW: 39 kDa/40 kDa/42 kDa/45 kDa

Gene ID: 5817

UniProt: P15151

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Cancer Immune Checkpoints, SARS-CoV-2 Protein Interactome