Poliovirus Receptor antibody

Catalog No. ABIN7269431

The Rabbit Monoclonal anti-Poliovirus Receptor antibody is suitable to detect Poliovirus Receptor in samples from Human. It has been validated for WB.

Quick Overview for Poliovirus Receptor antibody (ABIN7269431)

Target: Poliovirus Receptor (PVR)

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Poliovirus Receptor antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Poliovirus Receptor Antibody

Purpose: CD155/PVR Rabbit mAb

Cross-Reactivity: Human

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: A synthesized peptide derived from human CD155/PVR

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for Poliovirus Receptor

Target: Poliovirus Receptor (PVR)

Alternative Name: PVR

Background: The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008],CD155, HVED, NECL5, Necl-5, PVS, TAGE4,CDs,Immunology & Inflammation,PVR

Molecular Weight: 70kDa

Gene ID: 5817

UniProt: P15151

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Cancer Immune Checkpoints, SARS-CoV-2 Protein Interactome