Browse our anti-Angiopoietin 2 (ANGPT2) Antibodies

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anti-Angiopoietin 2 Antibodies (ANGPT2)
On are 143 Angiopoietin 2 (ANGPT2) Antibodies from 24 different suppliers available. Additionally we are shipping Angiopoietin 2 Kits (93) and Angiopoietin 2 Proteins (44) and many more products for this protein. A total of 296 Angiopoietin 2 products are currently listed.
list all antibodies Gene Name GeneID UniProt
ANGPT2 11601 O35608
ANGPT2 285 O15123
ANGPT2 89805 O35462

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Most Popular Reactivities for anti-Angiopoietin 2 (ANGPT2) Antibodies

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anti-Mouse (Murine) Angiopoietin 2 Antibodies:

anti-Human Angiopoietin 2 Antibodies:

anti-Rat (Rattus) Angiopoietin 2 Antibodies:

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Top referenced anti-Angiopoietin 2 Antibodies

  1. Human Polyclonal Angiopoietin 2 Primary Antibody for FACS, IHC (p) - ABIN654062 : Morrissey, Dowell, Koreckij, Nguyen, Lakely, Fanslow, True, Corey, Vessella: Inhibition of angiopoietin-2 in LuCaP 23.1 prostate cancer tumors decreases tumor growth and viability. in The Prostate 2010 (PubMed)
    Show all 3 references for 654062

  2. Human Polyclonal Angiopoietin 2 Primary Antibody for EIA, IHC (p) - ABIN950412 : Vrbacky, Smolej, Vroblova, Pekova, Hrudkova, Cervinka, Pecka, Krejsek, Maly: Angiopoietin-2 mRNA expression is increased in chronic lymphocytic leukemia patients with poor prognostic features. in Hematology (Amsterdam, Netherlands) 2010 (PubMed)
    Show all 3 references for 950412

  3. Chicken Monoclonal Angiopoietin 2 Primary Antibody for ICC, IHC (fro) - ABIN259881 : Laquer, Dao, Pavlis, Nguyen, Chen, Harris, Rugg, Kelly: Immunohistochemistry of angiogenesis mediators before and after pulsed dye laser treatment of angiomas. in Lasers in surgery and medicine 2012 (PubMed)
    Show all 2 references for 259881

  4. Human Polyclonal Angiopoietin 2 Primary Antibody for IF (p), IHC (p) - ABIN671781 : Lv, Fan, Su: Is a swine model of arteriovenous malformation suitable for human extracranial arteriovenous malformation? A preliminary study. in Cardiovascular and interventional radiology 2013 (PubMed)
    Show all 2 references for 671781

  5. Human Polyclonal Angiopoietin 2 Primary Antibody for IHC, IHC (p) - ABIN4280609 : Zhou, Fang, Shang, Zhang, Sang, Xu, Yuan, Chen, Zheng, Zhang, Zhuang: MicroRNAs miR-125b and miR-100 suppress metastasis of hepatocellular carcinoma by disrupting the formation of vessels that encapsulate tumour clusters. in The Journal of pathology 2016 (PubMed)

  6. Human Polyclonal Angiopoietin 2 Primary Antibody for WB - ABIN1043684 : Davis, Aldrich, Jones, Acheson, Compton, Jain, Ryan, Bruno, Radziejewski, Maisonpierre, Yancopoulos: Isolation of angiopoietin-1, a ligand for the TIE2 receptor, by secretion-trap expression cloning. in Cell 1997 (PubMed)

  7. Mouse (Murine) Polyclonal Angiopoietin 2 Primary Antibody for WB - ABIN95113 : Câmpean, Karpe, Haas, Atalla, Peters, Rupprecht, Liebner, Acker, Plate, Amann: Angiopoietin 1 and 2 gene and protein expression is differentially regulated in acute anti-Thy1.1 glomerulonephritis. in American journal of physiology. Renal physiology 2008 (PubMed)

More Antibodies against Angiopoietin 2 Interaction Partners

Zebrafish Angiopoietin 2 (ANGPT2) interaction partners

  1. Shear stress activated Ang-2 via canonical Wnt (show WNT2 Antibodies) signaling in vascular endothelial cells, and Wnt (show WNT2 Antibodies)-Ang-2 signaling is recapitulated in zebrafish embryos with a translational implication in vascular development and repair.

Mouse (Murine) Angiopoietin 2 (ANGPT2) interaction partners

  1. A balanced expression of the Ang1 (show ANGPT1 Antibodies)/Ang2 system is important for islet physiology. Ang-2 prevents beta-cell mass and islet vascular adaptation in response to HFD feeding with no major influence on glucose homeostasis

  2. These results underscore a pivotal role of Kaposi's sarcoma-associated herpesvirus -induced Ang-2 in KS tumor development by promoting both angiogenesis and inflammation.

  3. NDPKB (show NME1 Antibodies) is a protective factor in the retina, which controls Ang2 expression and the hexosamine pathway.

  4. miR (show MLXIP Antibodies)-150 is a novel suppressor of Ang2 generation with a key role in resolving vascular injury and reducing mortality resulting from sepsis.

  5. Ang-2 blockage was beneficial as it decreased fatty streak formation and plasma triglyceride levels, but had no adverse effect on pre-existing atherosclerosis in hypercholesterolemic mice.

  6. The results establish Ang2-mediated beta1-integrin activation as a promoter of endothelial destablization, explaining the controversial vascular functions of Ang1 (show ANGPT1 Antibodies) and Ang2.

  7. Alprostadil treatment can protect renal function by reducing proteinuria. These effects are mediated, at least in part, through down-regulation of Ang-2 and IL-18 (show IL18 Antibodies) expression

  8. ANG2 as the first essential regulator of the functionally important interendothelial cell-cell junctions that form during lymphatic development

  9. This study identifies angiopoietin-2 as a link between kidney fibrosis and arterial stiffness.

  10. vitamin D-VDR (show CYP27B1 Antibodies) signaling prevents lung injury by blocking the Ang-2-Tie-2 (show TEK Antibodies)-MLC kinase cascade and the renin (show REN Antibodies)-angiotensin system.

Human Angiopoietin 2 (ANGPT2) interaction partners

  1. This systematic review and meta-analysis suggested that serum Ang-2 levels might be a potential predictor for staging, and were associated with prognosis of lung cancer.

  2. Studied angiopoietin-1 (Ang-1 (show ANGPT1 Antibodies)) and angiopoietin-2 (Ang-2) within the intervertebral disc (IVD (show IVD Antibodies)) and elucidated their functions in the regulation of nucleus pulposus (NP) cells. Found the ratio of Ang-2/Ang-1 (show ANGPT1 Antibodies) in tissues from patients increased markedly with increasing age and level of degeneration of the IVD (show IVD Antibodies). Results indicate Ang-2 plays a role in suppressing cell adhesion&viability, and promotes the apoptosis of NP cells.

  3. ANG-1 (show ANGPT1 Antibodies), ANG-2 and TIE-2 (show TEK Antibodies) levels were significantly increased in placenta of non-complicated ART pregnancies compared to placentas from spontaneous conception.

  4. Analyses of human gastric cancer tissues showed a strong correlation between DARPP-32 (show PPP1R1B Antibodies) and ANGPT2. The role of DARPP-32 (show PPP1R1B Antibodies)-STAT3 (show STAT3 Antibodies) axis in regulating ANGPT2 in cancer cells to promote angiogenesis and tumorigenesis.

  5. ANGPT2 expression was upregulated in cerebral cavernous malformation lesions.

  6. In this study, we found that angiopoietins and Tie receptors were highly expressed in cervical cancer cells. Tie-2 (show TEK Antibodies) expression in tumor cells predicted poorer prognosis.Our data support that dual inhibition of Ang-1 (show ANGPT1 Antibodies) and Ang-2 may be an alternative target for anti-angiogenic adjuvant therapy in advanced or recurrent cervical squamous cell cancer.

  7. Linkage analysis identified a peak (LOD = 4.29) on chromosome 8p23. Follow-up association analysis identified two haplotypes in angiopoietin-2 (ANGPT2) that significantly contributed to the variation of SaO2 (P = 8 x 10-5) and accounted for a portion of the linkage evidence.

  8. Blood ANGPT2 was significantly higher in chronic hepatitis C patients with liver fibrosis compared to those without fibrosis.

  9. This study reveals ANGPT2 as a new susceptibility gene for nAMD and PCV, and it may affect disease susceptibility in association with CFH (show CFH Antibodies).

  10. We could therefore conclude that angiogenesis is an important event in the development of common skin warts, and the upregulation of both Ang1 (show ANGPT1 Antibodies) and -2 and their binding receptor Tie2 (show TEK Antibodies) may play a role in the angiogenesis associated with the development of these lesions.

Pig (Porcine) Angiopoietin 2 (ANGPT2) interaction partners

  1. expression of angiopoietin 2 in the porcine metanephric kidney was observed in the podocytes of early developing glomeruli, but not in the cells near the glomerular hilus

  2. ANGPT2 remained upregulated during maturation of glomeruli, which may be explained by the continuous growth of the glomeruli, as observed by stereological examination.

Rabbit Angiopoietin 2 (ANGPT2) interaction partners

  1. forward mandibular positioning enhance the expression of Ang1 (show ANGPT1 Antibodies) and Ang2 in condylar cartilage.

  2. These results suggest that circulating Ang-2 participates in the pathogenesis of systemic inflammatory response syndrome after injury connected with early haemodynamic instability.

Cow (Bovine) Angiopoietin 2 (ANGPT2) interaction partners

  1. Hypoxic regulation of Ang-2 is HIF-dependent and demonstrate that HIF-1alpha (show HIF1A Antibodies) binds in human microvascular endothelial cells (HMVEC) to an evolutionary conserved Hypoxia-Responsive Element (HRE) located in the first intron of the Ang-2 gene.

  2. Activation of the PI3-K (show PIK3CA Antibodies)/Akt (show AKT1 Antibodies) pathway downregulates Angiopoietin-2 reveals an additional mechanism through which the PTEN (show PTEN Antibodies)/PI3-K (show PIK3CA Antibodies)/Akt (show AKT1 Antibodies) pathway could affect the angiogenic process.

  3. Ang2 produced by oscillatory shear stress in endothelial cells plays a critical role in migration/tubule formation. May have role in diseases with disturbed flow/angiogenesis.

  4. In mature and late regressing corpus luteum, high scores of Ang-2-immunopositive endothelial and smooth muscle cells were found.

Angiopoietin 2 (ANGPT2) Antigen Profile

Antigen Summary

The protein encoded by this gene is an antagonist of angiopoietin 1 (ANGPT1) and endothelial TEK tyrosine kinase (TIE-2, TEK). The encoded protein disrupts the vascular remodeling ability of ANGPT1 and may induce endothelial cell apoptosis. Three transcript variants encoding three different isoforms have been found for this gene.

Alternative names and synonyms associated with Angiopoietin 2 (ANGPT2)

  • angiopoietin 2b (angpt2b) antibody
  • angiopoietin-2 (ANG-2) antibody
  • angiopoietin 2 (ANGPT2) antibody
  • angiopoietin 2 (LOC100225992) antibody
  • angiopoietin 2 (Angpt2) antibody
  • AGPT2 antibody
  • Ang-2 antibody
  • ANG2 antibody
  • ANGIOPOIETIN-2 antibody
  • ANGPT2 antibody

Protein level used designations for anti-Angiopoietin 2 (ANGPT2) Antibodies

angiopoietin 2 , angiopoietin-2 , angiopoietin-2-like , ANG-2 , Tie2-ligand , angiopoietin-2B , angiopoietin-2a , Angiopoietin-2B (Ang-2B) , angiopoietin-2A

114408 Danio rerio
443224 Ovis aries
100051890 Equus caballus
100225992 Taeniopygia guttata
100404686 Callithrix jacchus
11601 Mus musculus
285 Homo sapiens
89805 Rattus norvegicus
396730 Sus scrofa
100353377 Oryctolagus cuniculus
395610 Gallus gallus
607616 Canis lupus familiaris
100716962 Cavia porcellus
282141 Bos taurus
497273 Ovis aries
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