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anti-Human BDNF antibody for Immunohistochemistry

Recommended BDNF Antibody (supplied by: Log in to see )

Antigen
Brain-Derived Neurotrophic Factor (BDNF) Antibodies
  • bdnf-A
  • BDNF
  • Bdnf
  • bdnf
  • ANON2
  • BULN2
  • brain-derived neurotrophic factor
  • brain derived neurotrophic factor
  • brain-derived neurotrophic factor-like
  • bdnf
  • bdnf-A
  • BDNF
  • Bdnf
  • bdnf-b
  • LOC100356949
Epitope
Middle Region
30
23
7
6
6
6
6
6
5
5
5
5
4
4
4
3
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
Reactivity
Dog (Canine), Human, Mouse (Murine), Rat (Rattus)
290
131
108
15
15
10
9
7
6
5
5
5
3
2
2
1
Host
Rabbit
232
84
10
10
9
5
Clonality
Polyclonal
Conjugate
This BDNF antibody is un-conjugated
32
21
14
5
4
4
4
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (IHC), Western Blotting (WB)
282
146
109
57
53
52
35
24
13
11
9
4
4
2
2
1
1
1
1
Options
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Catalog No. ABIN2777093
$ 289.00
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
8.71188 ABIN4899237 FACS IHC Chicken IgY AA 129-247 Log in to see Polyclonal 5
8.71188 ABIN1981374 IHC WB Rabbit IgG AA 206-236, C-Term Log in to see Polyclonal
8.71188 ABIN3030196 FACS IF IHC ELISA WB Rabbit Ig Fraction AA 206-236 Log in to see Polyclonal
8.71188 ABIN4283815 IHC IHC (p) WB Rabbit Log in to see Polyclonal
8.71188 ABIN2157889 FACS IHC ELISA WB Rabbit Ig Fraction Log in to see Polyclonal
8.71188 ABIN2404176 IHC WB Rabbit IgG Log in to see Polyclonal
8.71188 ABIN4892211 IHC WB Rabbit Log in to see Polyclonal
8.71188 ABIN2425611 IHC ELISA Rabbit IgG Log in to see Polyclonal
8.71188 ABIN285669 IHC ELISA WB Chicken IgY Log in to see Polyclonal
1 ABIN350451 IHC WB Rabbit N-Term Log in to see Polyclonal 7
1 ABIN1871274 IHC WB Rabbit IgG Log in to see Polyclonal
1 ABIN1171949 IHC ELISA WB Biotin Rabbit IgG AA 129-247 Log in to see Polyclonal
1 ABIN4283827 FACS ICC IF IHC IHC (p) WB Mouse IgG2a kappa Log in to see 14C8-1D9
1 ABIN409162 ICC IF IHC IHC (fro) WB Rabbit Log in to see Polyclonal
1 ABIN1584074 IHC ELISA WB Rabbit Middle Region Log in to see Polyclonal
1 ABIN1077869 ICC IHC IP WB Rabbit IgG AA 129-247 Log in to see Polyclonal
1 ABIN3021893 IHC WB Rabbit IgG Log in to see Polyclonal
1 ABIN409229 ICC IHC (fro) IF IHC WB Rabbit Log in to see Polyclonal
1 ABIN465693 IHC Neut ELISA WB Rabbit Log in to see Polyclonal
1 ABIN350456 IHC WB Sheep IgG N-Term Log in to see Polyclonal 7

Top referenced anti-BDNF antibody for Immunohistochemistry

  • Human Polyclonal BDNF Primary Antibody for FACS, IHC - ABIN4899237 (5 Publications): Xapelli, Bernardino, Ferreira, Grade, Silva, Salgado, Cavadas, Grouzmann, Poulsen, Jakobsen, Oliveira, Zimmer, Malva: Interaction between neuropeptide Y (NPY) and brain-derived neurotrophic factor in NPY-mediated neuroprotection against excitotoxicity: a role for microglia. in The European journal of neuroscience 2008 (PubMed)

  • Dog (Canine) Polyclonal BDNF Primary Antibody for IHC, WB - ABIN2777093 (3 Publications): Hashimoto, Moriguchi, Yamashita, Mori, Nemoto, Okada, Hori, Noguchi, Kunugi, Ohnishi: Dose-dependent effect of the Val66Met polymorphism of the brain-derived neurotrophic factor gene on memory-related hippocampal activity. in Neuroscience research 2008 (PubMed)

Similar anti-BDNF Antibodies

Application / Reactivity Human Rat (Rattus) Dog (Canine) Mouse (Murine)
Immunofluorescence (fixed cells) (IF/ICC) 1 Antibodies 1 Antibodies 1 Antibodies 1 Antibodies
Western Blotting (WB) 227 Antibodies 86 Antibodies 100 Antibodies 13 Antibodies
Transfected Cell Culture (TCC) 1 Antibodies
Proximity Ligation Assay (PLA) 1 Antibodies
Neutralization (Neut) 4 Antibodies
Immunoprecipitation (IP) 17 Antibodies 4 Antibodies 8 Antibodies 1 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 49 Antibodies 12 Antibodies 27 Antibodies

General

Antigen Brain-Derived Neurotrophic Factor (BDNF) Antibodies
Epitope Middle Region
(30), (23), (7), (6), (6), (6), (6), (6), (5), (5), (5), (5), (4), (4), (4), (3), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Dog (Canine), Human, Mouse (Murine), Rat (Rattus)
(290), (131), (108), (15), (15), (10), (9), (7), (6), (5), (5), (5), (3), (2), (2), (1)
Host Rabbit
(232), (84), (10), (10), (9), (5)
Clonality
Polyclonal
Conjugate This BDNF antibody is un-conjugated
(32), (21), (14), (5), (4), (4), (4), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (IHC), Western Blotting (WB)
(282), (146), (109), (57), (53), (52), (35), (24), (13), (11), (9), (4), (4), (2), (2), (1), (1), (1), (1)
Pubmed 3 references available
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Product Details anti-BDNF Antibody

Target Details BDNF Application Details Handling References for anti-BDNF Antibody (ABIN2777093) Images
Blocking Peptide Blocking peptide for this product available: ABIN973798
Sequence EWVTAADKKT AVDMSGGTVT VLEKVPVSKG QLKQYFYETK CNPMGYTKEG
Predicted Reactivity African clawed frog : 100 %, Bovine : 100 %, Dog : 100 %, Guinea pig : 100 %, Horse : 100 %, Human : 100 %, Mouse : 100 %, Pig : 100 %, Rat : 100 %
Characteristics This is a rabbit polyclonal antibody against BDNF. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the middle region of human BDNF

Target Details BDNF

Product Details anti-BDNF Antibody Application Details Handling References for anti-BDNF Antibody (ABIN2777093) Images back to top
Antigen
Alternative Name BDNF (BDNF Antibody Abstract)
Background BDNF is a member of the nerve growth factor family. It is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. Expression BDNF is reduced in both Alzheimer's and Huntington disease patients. BDNF may play a role in the regulation of stress response and in the biology of mood disorders.The protein encoded by this gene is a member of the nerve growth factor family. It is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. Expression of this gene is reduced in both Alzheimer's and Huntington disease patients. This gene may play a role in the regulation of stress response and in the biology of mood disorders. Multiple transcript variants encoding distinct isoforms have been described for this gene, but the full-length nature of only some could be determined.
Molecular Weight 27 kDa
Gene ID 627
NCBI Accession NM_001709, NP_001700
UniProt P23560
Research Area Cardiovascular, Atherosclerosis, Alzheimer's Disease, Hormones
Pathways RTK Signaling

Application Details

Product Details anti-BDNF Antibody Target Details BDNF Handling References for anti-BDNF Antibody (ABIN2777093) Images back to top
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 247 AA

Restrictions For Research Use only

Handling

Product Details anti-BDNF Antibody Target Details BDNF Application Details References for anti-BDNF Antibody (ABIN2777093) Images back to top
Format Liquid
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage 4 °C,-20 °C
Storage Comment For short term use, store at 2-8 °C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

References for anti-BDNF Antibody (ABIN2777093)

Product Details anti-BDNF Antibody Target Details BDNF Application Details Handling Images back to top
Product cited in:

Vassoler, White, Schmidt, Sadri-Vakili, Pierce: "Epigenetic inheritance of a cocaine-resistance phenotype." in: Nature neuroscience, Vol. 16, Issue 1, pp. 42-7, 2012

McCarthy, Zhang, Darnell, Sangrey, Yanagawa, Sadri-Vakili, Bhide: "Cocaine alters BDNF expression and neuronal migration in the embryonic mouse forebrain." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 31, Issue 38, pp. 13400-11, 2011

Background publications

Hashimoto, Moriguchi, Yamashita, Mori, Nemoto, Okada, Hori, Noguchi, Kunugi, Ohnishi: "Dose-dependent effect of the Val66Met polymorphism of the brain-derived neurotrophic factor gene on memory-related hippocampal activity." in: Neuroscience research, Vol. 61, Issue 4, pp. 360-7, 2008

Images

Product Details anti-BDNF Antibody Target Details BDNF Application Details Handling References for anti-BDNF Antibody (ABIN2777093) back to top
Supplier Images
Western Blotting (WB) image for anti-BDNF antibody (Brain-Derived Neurotrophic Factor) (Middle Region) (ABIN2777093) anti-Brain-Derived Neurotrophic Factor (BDNF) (Middle Region) antibody
Immunohistochemistry (IHC) image for anti-BDNF antibody (Brain-Derived Neurotrophic Factor) (Middle Region) (ABIN2777093) anti-Brain-Derived Neurotrophic Factor (BDNF) (Middle Region) antibody (Image 2)
Immunohistochemistry (IHC) image for anti-BDNF antibody (Brain-Derived Neurotrophic Factor) (Middle Region) (ABIN2777093) anti-Brain-Derived Neurotrophic Factor (BDNF) (Middle Region) antibody (Image 3)