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anti-Mouse (Murine) FGF2 Antibodies:
anti-Rat (Rattus) FGF2 Antibodies:
anti-Human FGF2 Antibodies:
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Guinea Pig Polyclonal FGF2 Primary Antibody for IF (cc), IF (p) - ABIN726425
Pan, Wang, Xiang, Shao: Delta-like 1 serves as a new target and contributor to liver fibrosis down-regulated by mesenchymal stem cell transplantation. in The Journal of biological chemistry 2011
Show all 12 Pubmed References
Chicken Monoclonal FGF2 Primary Antibody for IF, IP - ABIN967725
Estival, Monzat, Miquel, Gaubert, Hollande, Korc, Vaysse, Clemente: Differential regulation of fibroblast growth factor (FGF) receptor-1 mRNA and protein by two molecular forms of basic FGF. Modulation of FGFR-1 mRNA stability. in The Journal of biological chemistry 1996
Show all 5 Pubmed References
Chicken Monoclonal FGF2 Primary Antibody for IF, IP - ABIN967726
Fox, Shanley: Antisense inhibition of basic fibroblast growth factor induces apoptosis in vascular smooth muscle cells. in The Journal of biological chemistry 1996
Show all 5 Pubmed References
Human Polyclonal FGF2 Primary Antibody for ELISA, IHC (p) - ABIN3042812
Wang, Wang, Yao, Wu, Tang, Gu, Li: The fibroblast growth factor-2 arrests Mycobacterium avium sp. paratuberculosis growth and immunomodulates host response in macrophages. in Tuberculosis (Edinburgh, Scotland) 2015
Show all 3 Pubmed References
Human Monoclonal FGF2 Primary Antibody for IHC, ELISA - ABIN969137
Romanov, James, Sherrington, Pettitt: Basic fibroblast growth factor suppresses p53 activation in the neoplastic cells of a proportion of patients with chronic lymphocytic leukaemia. in Oncogene 2005
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Human Polyclonal FGF2 Primary Antibody for WB - ABIN3042390
Zhou, Ma, Si, Li, Xu, Tu, Wang: MicroRNA-503 targets FGF2 and VEGFA and inhibits tumor angiogenesis and growth. in Cancer letters 2013
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Human Monoclonal FGF2 Primary Antibody for IHC, ELISA - ABIN966137
Kim, Shin, Choi, Kim, Ahn, Lee, Park, Kim, Mok, Nam: A preliminary results of a randomized trial comparing monthly 5-flourouracil and cisplatin to weekly cisplatin alone combined with concurrent radiotherapy for locally advanced cervical cancer. in Cancer research and treatment : official journal of Korean Cancer Association 2009
Show all 2 Pubmed References
Human Monoclonal FGF2 Primary Antibody for IHC (fro), ELISA - ABIN2473612
Kalsheker, Watkins, Hill, Morgan, Stockley, Fick: Independent mutations in the flanking sequence of the alpha-1-antitrypsin gene are associated with chronic obstructive airways disease. in Disease markers 1991
Show all 4 Pubmed References
Cow (Bovine) Polyclonal FGF2 Primary Antibody for IHC (p), IHC - ABIN269699
de Ruijter-Villani, van Boxtel, Stout: Fibroblast growth factor-2 expression in the preimplantation equine conceptus and endometrium of pregnant and cyclic mares. in Theriogenology 2013
Show all 2 Pubmed References
Human Monoclonal FGF2 Primary Antibody for IF, IHC - ABIN2452348
Pickard, Adams, Barraud, Chari: Using magnetic nanoparticles for gene transfer to neural stem cells: stem cell propagation method influences outcomes. in Journal of functional biomaterials 2015
Thus, FGF-2 levels in hESCs culture systems can be manipulated to generate cells with longer telomere which would be advantageous in the applications of hESCs in regenerative medicine.
Low FGF2 expression is associated with cardiac ischemia and systolic dysfunction.
Mechanical strain stimulates vasculogenesis of embryonic stem cells by the intracellular messengers ROS (show ROS1 Antibodies), NO and calcium as well as by upregulation of angiogenesis guidance molecules and the angiogenic growth factors VEGF (show VEGFA Antibodies), FGF-2 and PDGF (show PDGFA Antibodies)-BB.
FGFR (show FGFR2 Antibodies) Inhibitor Ameliorates Hypophosphatemia and Impaired Engrailed-1/Wnt (show WNT2 Antibodies) Signaling in FGF2 High Molecular Weight Isoform
data suggest that FGF2 levels are critically related to anxiety behavior and hypothalamic pituitary- adrenal axis activity, likely through modulation of hippocampal glucocorticoid receptor (show NR3C1 Antibodies) expression, an effect that is likely receptor mediated, albeit not by FGFR1 (show FGFR1 Antibodies), FGFR2 (show FGFR2 Antibodies), and FGFR3 (show FGFR3 Antibodies).
The differentiation of ERF-overexpressing trophoblast stem cell lines also suggests that ERF may have an FGF2-independent effect during the commitment towards syncytiotrophoblasts.
Novel VF-Trap fusion protein on blockage of VEGF (show VEGFA Antibodies) and FGF-2 activity to prevent angiogenesis.
FGF2 is an extracellular inducer of COUP-TFII (show NR2F2 Antibodies) expression and may suppress the osteogenic potential of mesenchymal cells by inducing COUP-TFII (show NR2F2 Antibodies) expression prior to the onset of osteogenic differentiation
clearly demonstrate the different specificity of FGF12 (show FGF12 Antibodies)-FGFR1c2 and FGF22 (show FGF22 Antibodies)-FGFR1c2 for well defined HS structures and suggest that it is now possible to chemoenzymatically synthesize precise HS polysaccharides that can selectively mediate growth factor signaling
These results support that controlling the aberrant expression of TGF-beta1 (show TGFB1 Antibodies) and FGF-2 via inhibition of Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) signaling could serve as a potential therapeutic strategy for pulmonary fibrosis.
Results uncover a novel Sdc2 (show SDC2 Antibodies)-Tbx16-Fgf2 pathway that regulates epithelial cell morphogenesis.
Taken together, Staphylococcus aureus induces TGF-beta1 (show TGFB1 Antibodies) and bFGF expression through the activation of AP-1 (show JUN Antibodies) and NF-kappaB (show NFKB1 Antibodies) in bovine mammary gland fibroblasts.
Data suggest THBS1 (thrombospondin-1 (show THBS1 Antibodies)) expression predominates in luteal endothelial cells; THBS2 (show THBS2 Antibodies) expression predominates in luteinized granulosa cells. Luteinizing signals down-regulate expression of THBS1 (show THBS1 Antibodies)/THBS2 (show THBS2 Antibodies) but up-regulate expression of FGF2.
Mixed populations of luteal cells were treated with SU1498 (VEGF receptor 2 inhibitor) or SU5402 (FGF receptor 1 inhibitor) or control on days 0-3, 3-6 or 6-9 to determine the role of FGF2 and VEGFA (show VEGFA Antibodies) during these specific windows.
FGF2 was crucial for luteal endothelial network formation.
Associations between reproduction and milk traits, and polymorphisms at the STAT5A (show STAT5A Antibodies) and FGF2 gene loci, were found with STAT5A (show STAT5A Antibodies) polymorphism for age at first calving (suggestive effect; P =0.077) and lactation milk yield (significant effect; P<0.05).
FGF2 and FGF10 (show FGF10 Antibodies) regulate migratory activity of ovine trophoblast cells through MAPK (show MAPK1 Antibodies)-dependent pathways.
investigation of signaling mechanisms used by FGF2 to regulate interferon-tau (IFNT) production in trophoblasts: several lines of evidence suggest that FGF2 regulates IFNT production in trophoblasts by acting through protein kinase C-delta (show PKCd Antibodies)
Alterations in the expression of VEGF-A (show VEGFA Antibodies) and bFGF systems suggest that angiogenic factors are involved in abnormal placental development in cloned gestations, contributing to impaired fetal development and poor survival rates.
bFGF is oxidized by lysyl oxidase (show LOX Antibodies)
vascular endothelial growth factor indirectly stimulates smooth muscle cell proliferation and migration through the modulation of basic fibroblast growth factor and transforming growth factor beta(1 (show TGFB1 Antibodies)) released by endothelial cells
Report no relationship between serum bFGF levels and ovarian cancer microvessel density and tumor bFGF expression.
High FGF2 expression is associated with ovarian cancer.
The antitumor activity of scopoletin may be due to its strong anti-angiogenic effect, which may be mediated by its effective inhibition of ERK1 (show MAPK3 Antibodies), VEGF-A (show VEGFA Antibodies), and FGF-2.
TGF-beta (show TGFB1 Antibodies), bFGF and epimorphin (show STX2 Antibodies) in the extracellular microenvironment cooperatively affect HSF (show HSF1 Antibodies) behaviors under the control of a highly sulfated (show SULF1 Antibodies) chondroitin sulfate
High FGF2 expression is associated with lung cancer.
miR (show MLXIP Antibodies)-205 enhances chemosensitivity of breast cancer cells to TAC (show IL2RA Antibodies) docetaxol, doxorubicin plus cyclophosphamide) by suppressing both VEGFA (show VEGFA Antibodies) and FGF2, leading to evasion of apoptosis.
analyses identified a new bFGF-regulating mechanism by which hedgehog (show SHH Antibodies) signaling regulates human fibroblast migration; this data opens a new avenue for the wound healing therapy
results show that HMGA2 expression is associated with highly proliferating MSCs, is tightly regulated by FGF-2, and is involved in both proliferation and adipogenesis of Mesenchymal stem cells.
FGF2-p(SS-co-PEGMA)-b-VS stimulated endothelial cell sprouting 250% better than FGF2 at low concentration. These data verify that this rationally designed protein-block copolymer conjugate enhances receptor binding, cellular processes such as migration and tube-like formation, and stability, and suggest that it may be useful for applications in biomaterials, tissue regeneration, and wound healing.
Continuous passive motion can promote b-FGF expression to enhance type III collagen (show COL3A1 Antibodies) synthesis at the tendon-bone interface in early stage of tendon-bone repair following acute rupture of supraspinatus tendon in rabbits.
Fibroblast growth factor-2 promotes in vitro heart valve interstitial cell repair through the Akt1 (show AKT1 Antibodies) pathway.
The overlapping relationships of 3'UTR (show UTS2R Antibodies) ends between NUDT6 (show NUDT6 Antibodies) and FGF-2 genes, were analyzed.
FGF2 in porcine ovary may be important for the growth of more follicles due to the localisation and concentration difference between stroma and follicle tissue.
By inducing the release of an endothelial elastase, shear stress induces an integrin-dependent release of FGF-2 from endothelial cells.
qPCR analysis demonstrated an increase in FGF-2 mRNA levels beginning on day 75 and on day 114 of pregnancy.
FGF2 activates FGFR (show FGFR2 Antibodies) which then represses the fibroblast activation of valvular interstitial cells.
FGF2 effectively blocks transforming growth factor-beta1 (TGF-beta1 (show TGFB1 Antibodies))-mediated myofibroblast activation
upregulation of TGFalpha or FGF2 expression is not a pre-requisite for enhanced testicular growth and increased Sertoli cell proliferation that occurs subsequent to hemicastration in the neonatal boar
These results suggest that bFGF activation of neuronal FGFR1 (show FGFR1 Antibodies) generates filopodial processes in neurons that promote nerve-muscle interaction and facilitate NMJ establishment.
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF.
, basic fibroblast growth factor
, heparin-binding growth factor 2
, fibroblast growth factor 2
, basic fibroblast growth factor bFGF
, Basic fibroblast growth factor
, Heparin-binding growth factor 2