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anti-Rat (Rattus) FGF2 antibody for Immunoprecipitation

Recommended FGF2 Antibody (supplied by: Log in to see )

Antigen
Fibroblast Growth Factor 2 (Basic) (FGF2) Antibodies
  • bFGF
  • BFGF
  • Fgf-2
  • FGF-2
  • Fgfb
  • FGFB
  • HBGF-2
Epitope
AA 1-155
14
13
12
12
10
8
8
6
4
3
3
3
3
2
2
2
1
1
1
1
1
1
1
1
Reactivity
Chicken, Dog (Canine), Human, Mouse (Murine), Rat (Rattus)
255
54
39
18
16
9
4
2
1
1
1
Host
Mouse
176
106
6
6
1
1
Clonality
Monoclonal
Conjugate
This FGF2 antibody is un-conjugated
28
16
11
6
5
5
1
1
1
1
1
1
1
1
1
1
1
Application
Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
194
167
90
34
25
20
18
17
14
11
11
10
6
5
3
2
1
1
1
1
1
1
1
1
1
1
Supplier
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Catalog No. ABIN967725
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Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.00089235755 ABIN967726 IF IP IHC WB Mouse IgG2a AA 1-155 Log in to see 6-basic FGF 5
0.00089235755 ABIN1690052 IP Magnetic Particles Rabbit Log in to see Polyclonal
0.00089235755 ABIN1690400 IP Sepharose Rabbit Log in to see Polyclonal

Top referenced anti-FGF2 antibody for Immunoprecipitation

Similar anti-FGF2 Antibodies

Application / Reactivity Human Mouse (Murine) Rat (Rattus) Chicken Dog (Canine)
Western Blotting (WB) 172 Antibodies 29 Antibodies 20 Antibodies 5 Antibodies 3 Antibodies
Transfected Cell Culture (TCC) 1 Antibodies
Radioimmunoassay (RIA) 3 Antibodies 2 Antibodies 2 Antibodies
Radial Immunodiffusion (RID) 1 Antibodies
Neutralization (Neut) 21 Antibodies
Immunostaining (ISt) 1 Antibodies
Immunoprecipitation (IP) 21 Antibodies 2 Antibodies 2 Antibodies 2 Antibodies 4 Antibodies
Immunohistochemistry (Paraformaldehyde) (IHC (pfa)) 1 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 29 Antibodies 5 Antibodies

General

Antigen Fibroblast Growth Factor 2 (Basic) (FGF2) Antibodies
Epitope AA 1-155
(14), (13), (12), (12), (10), (8), (8), (6), (4), (3), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Chicken, Dog (Canine), Human, Mouse (Murine), Rat (Rattus)
(255), (54), (39), (18), (16), (9), (4), (2), (1), (1), (1)
Host Mouse
(176), (106), (6), (6), (1), (1)
Clonality (Clone)
Monoclonal   ( )
Conjugate This FGF2 antibody is un-conjugated
(28), (16), (11), (6), (5), (5), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
(194), (167), (90), (34), (25), (20), (18), (17), (14), (11), (11), (10), (6), (5), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Pubmed 5 references available
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Product Details anti-FGF2 Antibody

Target Details FGF2 Application Details Handling References for anti-FGF2 Antibody (ABIN967725) Images
Cross-Reactivity Mouse (Murine), Rat (Rattus), Dog (Canine), Chicken
Characteristics 1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Please refer to us for technical protocols.
Purification The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
Immunogen Human bFGF aa. 1-155
Clone 6-basic FGF
Isotype IgG2a

Target Details FGF2

Product Details anti-FGF2 Antibody Application Details Handling References for anti-FGF2 Antibody (ABIN967725) Images back to top
Antigen
Alternative Name basic FGF (FGF2 Antibody Abstract)
Background Basic Fibroblast Growth Factor (bFGF) is a family member of the cell-differentiating and growth promoting factors. Basic FGF exists as multiple isoforms ranging from 18-24kDa that are derived from a single mRNA species under unique translational conditions. The 18kDa isoform is primarily cytosolic, but is also secreted and may form reservoirs of bFGF in the extracellular matrix. In contrast, the larger isoforms are predominantly nuclear. At the cellular level, bFGF is a potent mitogen and promotes cell survival by inhibiting apoptosis. At the tissue level, it is involved in wound repair and induces angiogenesis. In addition, bFGF is a significant target in cancer research because it is over-expressed in some cancers and may enhance a tumor's metastatic potential.
Molecular Weight 18-24 kDa
Pathways RTK Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway

Application Details

Product Details anti-FGF2 Antibody Target Details FGF2 Handling References for anti-FGF2 Antibody (ABIN967725) Images back to top
Comment

Related Products: ABIN968545, ABIN967389

Restrictions For Research Use only

Handling

Product Details anti-FGF2 Antibody Target Details FGF2 Application Details References for anti-FGF2 Antibody (ABIN967725) Images back to top
Format Liquid
Concentration 250 μg/mL
Buffer Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store undiluted at -20°C.

References for anti-FGF2 Antibody (ABIN967725)

Product Details anti-FGF2 Antibody Target Details FGF2 Application Details Handling Images back to top
Product cited in:

Yaccoby, Johnson, Mahaffey, Wezeman, Barlogie, Epstein: "Antimyeloma efficacy of thalidomide in the SCID-hu model." in: Blood, Vol. 100, Issue 12, pp. 4162-8, 2002

Peng, Moffett, Myers, Fang, Stachowiak, Maher, Kratz, Hines, Fluharty, Mizukoshi, Bloom, Stachowiak: "Novel nuclear signaling pathway mediates activation of fibroblast growth factor-2 gene by type 1 and type 2 angiotensin II receptors." in: Molecular biology of the cell, Vol. 12, Issue 2, pp. 449-62, 2001

Estival, Monzat, Miquel, Gaubert, Hollande, Korc, Vaysse, Clemente: "Differential regulation of fibroblast growth factor (FGF) receptor-1 mRNA and protein by two molecular forms of basic FGF. Modulation of FGFR-1 mRNA stability." in: The Journal of biological chemistry, Vol. 271, Issue 10, pp. 5663-70, 1996

Fox, Shanley: "Antisense inhibition of basic fibroblast growth factor induces apoptosis in vascular smooth muscle cells." in: The Journal of biological chemistry, Vol. 271, Issue 21, pp. 12578-84, 1996

Stachowiak, Moffett, Joy, Puchacz, Florkiewicz, Stachowiak: "Regulation of bFGF gene expression and subcellular distribution of bFGF protein in adrenal medullary cells." in: The Journal of cell biology, Vol. 127, Issue 1, pp. 203-23, 1994

Images

Product Details anti-FGF2 Antibody Target Details FGF2 Application Details Handling References for anti-FGF2 Antibody (ABIN967725) back to top
Supplier Images
Western Blotting (WB) image for anti-FGF2 antibody (Fibroblast Growth Factor 2 (Basic)) (AA 1-155) (ABIN967725) Western blot analysis for basic FGF on a HeLa cell lysate (Human cervical epitheloid ...
 image for anti-FGF2 antibody (Fibroblast Growth Factor 2 (Basic)) (AA 1-155) (ABIN967725) Immnuofluroescence staining of human fibroblasts.